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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS16
All Species:
16.67
Human Site:
S949
Identified Species:
40.74
UniProt:
Q8TE57
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE57
NP_620687.2
1224
136203
S949
T
C
G
G
G
A
Q
S
R
P
V
Q
C
T
R
Chimpanzee
Pan troglodytes
XP_526829
1072
119415
R819
S
G
T
T
F
D
Y
R
R
S
Y
N
E
P
E
Rhesus Macaque
Macaca mulatta
XP_001082662
1224
136022
S949
T
C
G
G
G
A
Q
S
R
P
V
Q
C
T
R
Dog
Lupus familis
XP_545184
1278
141611
S1003
T
C
G
G
G
T
Q
S
R
P
V
Q
C
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z28
1222
136264
S947
T
C
G
G
G
T
Q
S
R
P
V
R
C
T
R
Rat
Rattus norvegicus
Q1EHB3
1595
175796
A1169
D
G
M
V
T
S
V
A
P
G
N
P
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511434
1195
134964
F920
T
C
G
L
G
E
Q
F
R
L
I
H
C
M
Q
Chicken
Gallus gallus
XP_424749
1118
125075
K863
T
C
A
G
G
V
Q
K
Q
E
V
V
C
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919066
1234
137743
T953
T
C
G
G
G
Q
Q
T
R
N
I
R
C
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780466
1202
135114
R931
C
G
S
G
R
Q
K
R
K
V
V
C
I
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
97.7
81.4
N.A.
82.6
30.5
N.A.
76.6
35.7
N.A.
56.4
N.A.
N.A.
N.A.
N.A.
46.3
Protein Similarity:
100
87.3
98.4
87
N.A.
89
43
N.A.
84.9
53.2
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
62
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
0
N.A.
46.6
53.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
13.3
N.A.
60
60
N.A.
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
20
0
10
0
0
0
0
0
0
0
% A
% Cys:
10
70
0
0
0
0
0
0
0
0
0
10
70
0
0
% C
% Asp:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
0
0
10
10
20
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
30
60
70
70
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
10
0
0
0
0
20
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
10
0
0
0
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
40
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
20
70
0
10
0
0
30
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
20
70
0
0
20
0
0
60
% R
% Ser:
10
0
10
0
0
10
0
40
0
10
0
0
0
0
0
% S
% Thr:
70
0
10
10
10
20
0
10
0
0
0
0
0
40
0
% T
% Val:
0
0
0
10
0
10
10
0
0
10
60
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _