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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS19
All Species:
15.45
Human Site:
Y222
Identified Species:
42.5
UniProt:
Q8TE59
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE59
NP_598377.3
1207
134062
Y222
P
P
D
A
G
C
F
Y
T
G
A
V
L
R
H
Chimpanzee
Pan troglodytes
XP_517910
1207
133897
Y222
P
P
D
A
G
C
F
Y
T
G
A
V
L
R
H
Rhesus Macaque
Macaca mulatta
XP_001099247
1207
133840
Y222
P
P
D
A
G
C
F
Y
T
G
A
V
L
R
H
Dog
Lupus familis
XP_545825
1181
130543
Y210
R
P
A
E
L
C
F
Y
S
G
R
V
L
G
H
Cat
Felis silvestris
Mouse
Mus musculus
P59509
1210
134542
Y225
L
P
D
A
S
C
F
Y
T
G
T
V
L
R
H
Rat
Rattus norvegicus
NP_001101903
825
90801
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508084
930
104524
Chicken
Gallus gallus
XP_413968
1004
113534
E78
Y
R
R
K
R
S
V
E
E
K
I
T
E
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338858
701
77870
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
51.2
N.A.
87.5
57.8
N.A.
44.4
71.7
N.A.
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99.3
67.1
N.A.
91.7
61.2
N.A.
58.5
78.4
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
80
0
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
60
N.A.
80
0
N.A.
0
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
45
0
0
0
0
0
0
34
0
0
0
12
% A
% Cys:
0
0
0
0
0
56
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
12
12
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
56
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
34
0
0
0
0
56
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
56
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
12
0
0
0
12
0
% K
% Leu:
12
0
0
0
12
0
0
0
0
0
0
0
56
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
12
12
0
12
0
0
0
0
0
12
0
0
45
0
% R
% Ser:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
45
0
12
12
0
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
56
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _