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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS18
All Species:
10.61
Human Site:
S228
Identified Species:
25.93
UniProt:
Q8TE60
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE60
NP_955387.1
1221
135167
S228
G
R
N
Y
P
G
Y
S
P
S
H
I
P
H
A
Chimpanzee
Pan troglodytes
XP_001143790
1221
135118
S228
G
R
N
Y
P
G
Y
S
P
S
H
I
P
H
A
Rhesus Macaque
Macaca mulatta
XP_001082662
1224
136022
H230
S
R
T
W
E
L
A
H
Q
P
L
H
S
S
D
Dog
Lupus familis
XP_546824
1540
170435
S546
S
G
R
S
S
G
H
S
P
T
H
T
P
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4VC17
1219
135211
S228
Q
R
T
Y
P
G
H
S
P
S
H
T
P
P
A
Rat
Rattus norvegicus
Q1EHB3
1595
175796
I320
P
Q
H
H
D
T
A
I
L
L
T
R
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511434
1195
134964
N210
Q
R
L
H
S
G
F
N
L
R
H
L
Q
K
Q
Chicken
Gallus gallus
XP_424749
1118
125075
K192
G
H
P
H
V
I
Y
K
K
S
T
M
R
Q
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919066
1234
137743
Y232
R
F
K
S
S
N
P
Y
E
D
H
H
H
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780466
1202
135114
E212
E
K
K
G
H
H
R
E
R
L
R
E
H
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
55.5
71.2
N.A.
88.6
30.2
N.A.
57.3
36.9
N.A.
64.4
N.A.
N.A.
N.A.
N.A.
46.7
Protein Similarity:
100
99.5
70.7
75
N.A.
93.5
43.5
N.A.
72.3
53.5
N.A.
76.1
N.A.
N.A.
N.A.
N.A.
62.4
P-Site Identity:
100
100
6.6
33.3
N.A.
66.6
0
N.A.
20
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
46.6
N.A.
73.3
20
N.A.
46.6
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
10
0
0
0
10
10
% D
% Glu:
10
0
0
0
10
0
0
10
10
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
30
10
0
10
0
50
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
10
30
10
10
20
10
0
0
60
20
20
40
20
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
0
20
0
0
0
% I
% Lys:
0
10
20
0
0
0
0
10
10
0
0
0
10
10
0
% K
% Leu:
0
0
10
0
0
10
0
0
20
20
10
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
20
0
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
30
0
10
0
40
10
0
0
40
10
0
% P
% Gln:
20
10
0
0
0
0
0
0
10
0
0
0
10
10
10
% Q
% Arg:
10
50
10
0
0
0
10
0
10
10
10
10
10
10
0
% R
% Ser:
20
0
0
20
30
0
0
40
0
40
0
0
10
10
10
% S
% Thr:
0
0
20
0
0
10
0
0
0
10
20
20
0
0
10
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
30
0
0
30
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _