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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS18
All Species:
17.88
Human Site:
T466
Identified Species:
43.7
UniProt:
Q8TE60
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE60
NP_955387.1
1221
135167
T466
N
I
M
S
P
T
L
T
G
N
N
G
V
F
S
Chimpanzee
Pan troglodytes
XP_001143790
1221
135118
T466
N
I
M
S
P
T
L
T
G
N
N
G
V
F
S
Rhesus Macaque
Macaca mulatta
XP_001082662
1224
136022
A463
N
I
M
S
P
T
L
A
G
R
N
G
V
F
S
Dog
Lupus familis
XP_546824
1540
170435
T784
N
I
M
S
P
T
L
T
G
N
N
G
V
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4VC17
1219
135211
T466
N
I
M
S
P
T
L
T
G
N
N
G
V
F
S
Rat
Rattus norvegicus
Q1EHB3
1595
175796
H599
M
L
Y
K
G
K
L
H
K
W
V
P
V
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511434
1195
134964
A434
N
I
M
S
P
T
L
A
G
H
N
G
V
F
S
Chicken
Gallus gallus
XP_424749
1118
125075
N409
I
A
H
E
I
G
H
N
F
G
M
N
H
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919066
1234
137743
A472
N
I
M
S
P
T
L
A
G
N
N
G
V
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780466
1202
135114
S445
D
I
M
S
P
T
L
S
G
H
S
G
R
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
55.5
71.2
N.A.
88.6
30.2
N.A.
57.3
36.9
N.A.
64.4
N.A.
N.A.
N.A.
N.A.
46.7
Protein Similarity:
100
99.5
70.7
75
N.A.
93.5
43.5
N.A.
72.3
53.5
N.A.
76.1
N.A.
N.A.
N.A.
N.A.
62.4
P-Site Identity:
100
100
86.6
100
N.A.
100
13.3
N.A.
86.6
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
86.6
100
N.A.
100
26.6
N.A.
93.3
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
30
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
80
0
% F
% Gly:
0
0
0
0
10
10
0
0
80
10
0
80
0
0
10
% G
% His:
0
0
10
0
0
0
10
10
0
20
0
0
10
0
0
% H
% Ile:
10
80
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
90
0
0
0
0
0
0
10
0
% L
% Met:
10
0
80
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
70
0
0
0
0
0
0
10
0
50
70
10
0
0
10
% N
% Pro:
0
0
0
0
80
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
0
0
80
0
0
0
10
0
0
10
0
0
0
70
% S
% Thr:
0
0
0
0
0
80
0
40
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
80
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _