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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS18
All Species:
13.03
Human Site:
Y270
Identified Species:
31.85
UniProt:
Q8TE60
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE60
NP_955387.1
1221
135167
Y270
K
P
P
T
E
D
T
Y
L
R
F
D
E
Y
G
Chimpanzee
Pan troglodytes
XP_001143790
1221
135118
Y270
K
P
P
T
E
D
T
Y
L
R
F
D
E
Y
G
Rhesus Macaque
Macaca mulatta
XP_001082662
1224
136022
E270
D
L
F
I
L
P
D
E
Y
K
S
C
L
R
H
Dog
Lupus familis
XP_546824
1540
170435
Y588
K
P
P
T
E
D
T
Y
L
R
F
D
E
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q4VC17
1219
135211
Y270
K
P
P
A
E
D
A
Y
L
R
F
D
E
Y
G
Rat
Rattus norvegicus
Q1EHB3
1595
175796
H373
T
V
A
H
E
L
G
H
S
F
G
I
Q
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511434
1195
134964
L252
P
L
R
K
K
R
S
L
L
K
A
H
K
N
N
Chicken
Gallus gallus
XP_424749
1118
125075
P232
S
A
F
P
T
S
L
P
V
N
D
T
L
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919066
1234
137743
F274
K
P
P
T
E
D
H
F
V
M
P
D
E
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780466
1202
135114
N252
L
D
E
Y
P
D
A
N
G
S
S
I
Q
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
55.5
71.2
N.A.
88.6
30.2
N.A.
57.3
36.9
N.A.
64.4
N.A.
N.A.
N.A.
N.A.
46.7
Protein Similarity:
100
99.5
70.7
75
N.A.
93.5
43.5
N.A.
72.3
53.5
N.A.
76.1
N.A.
N.A.
N.A.
N.A.
62.4
P-Site Identity:
100
100
0
100
N.A.
86.6
6.6
N.A.
6.6
0
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
86.6
26.6
N.A.
33.3
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
20
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
10
0
0
0
60
10
0
0
0
10
50
0
0
10
% D
% Glu:
0
0
10
0
60
0
0
10
0
0
0
0
50
0
10
% E
% Phe:
0
0
20
0
0
0
0
10
0
10
40
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
40
% G
% His:
0
0
0
10
0
0
10
10
0
0
0
10
0
10
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
50
0
0
10
10
0
0
0
0
20
0
0
10
0
0
% K
% Leu:
10
20
0
0
10
10
10
10
50
0
0
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
10
% N
% Pro:
10
50
50
10
10
10
0
10
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% Q
% Arg:
0
0
10
0
0
10
0
0
0
40
0
0
0
10
10
% R
% Ser:
10
0
0
0
0
10
10
0
10
10
20
0
0
10
10
% S
% Thr:
10
0
0
40
10
0
30
0
0
0
0
10
0
10
0
% T
% Val:
0
10
0
0
0
0
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
40
10
0
0
0
0
40
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _