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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS18
All Species:
30
Human Site:
Y515
Identified Species:
73.33
UniProt:
Q8TE60
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE60
NP_955387.1
1221
135167
Y515
D
K
L
P
G
Q
I
Y
D
A
D
T
Q
C
K
Chimpanzee
Pan troglodytes
XP_001143790
1221
135118
Y515
D
K
L
P
G
Q
I
Y
D
A
D
T
Q
C
K
Rhesus Macaque
Macaca mulatta
XP_001082662
1224
136022
Y512
E
K
L
P
G
E
L
Y
D
A
N
T
Q
C
K
Dog
Lupus familis
XP_546824
1540
170435
Y833
D
K
L
P
G
Q
I
Y
D
A
D
T
Q
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q4VC17
1219
135211
Y515
D
K
L
P
G
Q
I
Y
D
A
D
M
Q
C
K
Rat
Rattus norvegicus
Q1EHB3
1595
175796
K687
H
T
V
S
R
T
F
K
E
A
E
G
M
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511434
1195
134964
Y483
E
K
L
P
G
E
L
Y
D
A
N
T
Q
C
K
Chicken
Gallus gallus
XP_424749
1118
125075
L457
R
D
Y
I
T
S
F
L
D
S
G
R
G
T
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919066
1234
137743
Y521
E
Q
L
P
G
Q
L
Y
D
A
D
I
Q
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780466
1202
135114
Y494
P
S
L
P
G
E
L
Y
S
A
D
Q
Q
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
55.5
71.2
N.A.
88.6
30.2
N.A.
57.3
36.9
N.A.
64.4
N.A.
N.A.
N.A.
N.A.
46.7
Protein Similarity:
100
99.5
70.7
75
N.A.
93.5
43.5
N.A.
72.3
53.5
N.A.
76.1
N.A.
N.A.
N.A.
N.A.
62.4
P-Site Identity:
100
100
73.3
100
N.A.
93.3
6.6
N.A.
73.3
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
100
13.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
10
% C
% Asp:
40
10
0
0
0
0
0
0
80
0
60
0
0
0
0
% D
% Glu:
30
0
0
0
0
30
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
80
0
0
0
0
0
10
10
10
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
40
0
0
0
0
10
0
0
0
% I
% Lys:
0
60
0
0
0
0
0
10
0
0
0
0
0
0
70
% K
% Leu:
0
0
80
0
0
0
40
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% N
% Pro:
10
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
50
0
0
0
0
0
10
80
0
10
% Q
% Arg:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
0
10
0
10
0
0
10
10
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
10
0
0
0
0
0
50
0
10
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
80
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _