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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L3
All Species:
8.48
Human Site:
S229
Identified Species:
31.11
UniProt:
Q8TE67
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE67
NP_078802.2
593
66861
S229
T
L
P
P
P
R
R
S
S
S
P
E
D
P
E
Chimpanzee
Pan troglodytes
XP_001164167
593
66888
S229
T
L
P
P
P
R
R
S
S
S
P
E
D
P
E
Rhesus Macaque
Macaca mulatta
XP_001096625
594
66911
P229
T
P
P
P
P
R
R
P
S
S
P
E
D
P
E
Dog
Lupus familis
XP_547239
614
69302
T229
T
L
P
P
P
R
R
T
P
S
P
E
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WL0
600
68197
R235
T
L
P
P
P
P
R
R
A
P
S
P
E
D
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510664
556
62861
P214
Y
N
P
P
P
Q
E
P
Q
P
P
Q
D
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666161
646
73168
Q263
T
K
T
P
P
H
K
Q
T
T
P
P
R
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
92.9
71.3
N.A.
72.5
N.A.
N.A.
43.8
N.A.
N.A.
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
95.6
80.2
N.A.
82.6
N.A.
N.A.
59.7
N.A.
N.A.
51.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
40
N.A.
N.A.
40
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
53.3
N.A.
N.A.
53.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
58
15
0
% D
% Glu:
0
0
0
0
0
0
15
0
0
0
0
58
15
0
86
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
0
0
0
15
0
0
0
0
0
0
0
0
% K
% Leu:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
86
100
100
15
0
29
15
29
86
29
0
58
15
% P
% Gln:
0
0
0
0
0
15
0
15
15
0
0
15
0
0
0
% Q
% Arg:
0
0
0
0
0
58
72
15
0
0
0
0
15
0
0
% R
% Ser:
0
0
0
0
0
0
0
29
43
58
15
0
15
0
0
% S
% Thr:
86
0
15
0
0
0
0
15
15
15
0
0
0
15
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _