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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN6 All Species: 31.52
Human Site: Y347 Identified Species: 57.78
UniProt: Q8TEA1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TEA1 NP_872349.1 469 51770 Y347 S V K E V A S Y Q P L Q R K L
Chimpanzee Pan troglodytes XP_507683 469 51748 Y347 S L K E V A S Y Q P L Q R K L
Rhesus Macaque Macaca mulatta XP_001094308 311 34278 V202 G I R M T E P V Y L S P S F D
Dog Lupus familis XP_544240 469 51842 Y347 T L K E V T S Y Q P L Q R K L
Cat Felis silvestris
Mouse Mus musculus Q7TS68 476 52260 Y347 T L K E V T S Y Q P L Q R K L
Rat Rattus norvegicus NP_001100837 476 52290 Y347 T L K E V T S Y Q P L Q R K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509484 466 50374 Y347 T L K E V T S Y P P L Q R R L
Chicken Gallus gallus XP_425980 469 51903 Y347 T L K E V T S Y Q P L Q R K L
Frog Xenopus laevis NP_001090297 467 51218 Y348 S L K E L T S Y Q P L Q R K L
Zebra Danio Brachydanio rerio XP_001919347 417 45924 S297 C N S I H A V S S D P A Q E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730761 439 47926 S321 I L L D A P C S G L G N R P Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001145845 585 64025 H474 T L E S L K K H S K Y Q R K M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 Q452 F I Q I P H L Q K Q L L L S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 64.3 88.2 N.A. 80 78.9 N.A. 68.2 73.7 68.8 48.8 N.A. 39.8 N.A. N.A. N.A.
Protein Similarity: 100 99.3 66 93.3 N.A. 87.8 88.4 N.A. 80.1 86.1 81.8 66 N.A. 56.5 N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 80 N.A. 80 80 N.A. 66.6 80 80 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 93.3 N.A. 86.6 93.3 93.3 20 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 28.8 N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. 45.1 N.A. N.A. 36.4 N.A.
P-Site Identity: N.A. 20 N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. 60 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 24 0 0 0 0 0 8 0 0 8 % A
% Cys: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 8 % D
% Glu: 0 0 8 62 0 8 0 0 0 0 0 0 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % G
% His: 0 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 16 0 16 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 62 0 0 8 8 0 8 8 0 0 0 62 0 % K
% Leu: 0 70 8 0 16 0 8 0 0 16 70 8 8 0 62 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 8 8 8 0 8 62 8 8 0 8 0 % P
% Gln: 0 0 8 0 0 0 0 8 54 8 0 70 8 0 8 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 77 8 0 % R
% Ser: 24 0 8 8 0 0 62 16 16 0 8 0 8 8 0 % S
% Thr: 47 0 0 0 8 47 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 54 0 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 8 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _