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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
26.67
Human Site:
S348
Identified Species:
48.89
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
S348
V
N
K
E
I
I
R
S
K
P
P
I
C
T
L
Chimpanzee
Pan troglodytes
XP_526648
893
100716
S348
V
N
K
E
I
I
R
S
K
P
P
I
C
T
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
S348
V
N
K
E
I
I
R
S
K
P
P
I
C
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
L250
P
E
N
V
I
N
I
L
K
K
C
L
T
F
H
Rat
Rattus norvegicus
NP_001127985
860
96794
E339
A
G
G
D
L
E
K
E
L
I
N
K
E
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
S353
V
N
K
E
I
I
R
S
K
P
P
V
C
T
L
Chicken
Gallus gallus
Q5F361
893
100434
S348
V
N
K
E
I
I
R
S
K
P
P
V
C
T
L
Frog
Xenopus laevis
NP_001087131
893
100210
S348
M
S
K
G
I
I
R
S
K
P
P
I
C
T
L
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
S348
T
N
Q
E
I
I
Q
S
K
P
P
I
C
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
V307
W
Q
L
A
G
G
D
V
Q
A
E
L
K
K
E
Honey Bee
Apis mellifera
XP_393033
792
90269
D280
L
W
Q
L
A
G
G
D
I
T
V
E
L
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
K360
D
L
E
G
E
L
R
K
K
G
L
L
R
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
0
N.A.
93.3
93.3
80
80
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
20
26.6
N.A.
100
100
93.3
93.3
N.A.
13.3
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
54
0
0
% C
% Asp:
8
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
47
8
8
0
8
0
0
8
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
8
16
8
16
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
62
54
8
0
8
8
0
39
0
8
8
% I
% Lys:
0
0
47
0
0
0
8
8
70
8
0
8
8
16
8
% K
% Leu:
8
8
8
8
8
8
0
8
8
0
8
24
8
0
54
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
47
8
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
54
54
0
0
0
0
% P
% Gln:
0
8
16
0
0
0
8
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
54
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
0
0
0
0
54
0
0
0
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
8
54
0
% T
% Val:
39
0
0
8
0
0
0
8
0
0
8
16
0
0
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _