KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
19.09
Human Site:
S723
Identified Species:
35
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
S723
P
P
K
P
S
S
D
S
S
G
G
R
S
S
A
Chimpanzee
Pan troglodytes
XP_526648
893
100716
S723
P
P
K
P
S
S
D
S
S
G
V
R
S
S
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
S723
P
P
K
P
T
S
D
S
N
G
I
R
S
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
M600
Y
L
T
V
F
S
Q
M
I
A
F
H
D
P
E
Rat
Rattus norvegicus
NP_001127985
860
96794
S690
P
R
P
A
S
E
S
S
A
V
R
S
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
P728
P
P
K
Q
T
I
D
P
S
G
G
R
N
S
A
Chicken
Gallus gallus
Q5F361
893
100434
S723
P
P
R
Q
A
N
E
S
N
G
T
R
S
S
M
Frog
Xenopus laevis
NP_001087131
893
100210
S723
V
P
K
Q
I
A
E
S
N
G
M
S
R
A
A
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
S723
P
N
K
P
P
S
E
S
N
S
F
G
K
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
V657
D
I
V
M
D
G
C
V
L
E
S
Q
K
M
Y
Honey Bee
Apis mellifera
XP_393033
792
90269
D630
F
S
D
L
P
E
I
D
I
E
L
C
V
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
E714
D
I
E
K
C
V
R
E
S
I
R
L
F
C
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
K344
K
V
I
H
R
D
I
K
P
Q
N
I
L
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
93.3
N.A.
73.3
N.A.
6.6
40
N.A.
66.6
46.6
33.3
33.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
86.6
N.A.
6.6
46.6
N.A.
80
80
60
53.3
N.A.
6.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
8
0
0
8
8
0
0
0
8
39
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
8
0
8
0
% C
% Asp:
16
0
8
0
8
8
31
8
0
0
0
0
8
0
8
% D
% Glu:
0
0
8
0
0
16
24
8
0
16
0
0
0
0
8
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
16
0
8
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
47
16
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
16
8
0
8
8
16
0
16
8
8
8
0
0
0
% I
% Lys:
8
0
47
8
0
0
0
8
0
0
0
0
16
8
0
% K
% Leu:
0
8
0
8
0
0
0
0
8
0
8
8
8
8
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
8
0
0
8
8
% M
% Asn:
0
8
0
0
0
8
0
0
31
0
8
0
8
0
16
% N
% Pro:
54
47
8
31
16
0
0
8
8
0
0
0
0
8
8
% P
% Gln:
0
0
0
24
0
0
8
0
0
8
0
8
0
0
0
% Q
% Arg:
0
8
8
0
8
0
8
0
0
0
16
39
8
0
0
% R
% Ser:
0
8
0
0
24
39
8
54
31
8
8
16
39
47
0
% S
% Thr:
0
0
8
0
16
0
0
0
0
0
8
0
0
8
8
% T
% Val:
8
8
8
8
0
8
0
8
0
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _