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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCK All Species: 31.82
Human Site: S890 Identified Species: 58.33
UniProt: Q8TEA7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TEA7 NP_001156907.1 893 100680 S890 T G L L T I P S P Q I _ _ _ _
Chimpanzee Pan troglodytes XP_526648 893 100716 S890 T G L L T I P S P Q I _ _ _ _
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545015 893 100744 S890 T G L L T V P S P Q I _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q8BM85 762 86353
Rat Rattus norvegicus NP_001127985 860 96794 S857 T G L L T V P S P Q I _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510722 898 101284 S895 T G L L T V P S P Q I _ _ _ _
Chicken Gallus gallus Q5F361 893 100434 S890 T G L L T V P S P Q I _ _ _ _
Frog Xenopus laevis NP_001087131 893 100210 S890 T G L L T V P S P Q I _ _ _ _
Zebra Danio Brachydanio rerio NP_001074106 893 100952 S890 T G L L T V P S P Q I _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572197 819 93251
Honey Bee Apis mellifera XP_393033 792 90269
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199652 877 98431
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32491 506 56739
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 96.7 N.A. 81 90.5 N.A. 90.3 87.1 81.5 76.7 N.A. 43.6 47.5 N.A. 55.2
Protein Similarity: 100 99.7 N.A. 98.8 N.A. 83.5 94.2 N.A. 94.5 92.8 90 87.6 N.A. 58.5 62.7 N.A. 70.8
P-Site Identity: 100 100 N.A. 90.9 N.A. 0 90.9 N.A. 90.9 90.9 90.9 90.9 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 0 100 N.A. 100 100 100 100 N.A. 0 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 32.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 0 0 62 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 62 62 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 62 0 62 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 62 0 0 0 0 0 0 0 % S
% Thr: 62 0 0 0 62 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 62 62 62 62 % _