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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCK All Species: 31.52
Human Site: T47 Identified Species: 57.78
UniProt: Q8TEA7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TEA7 NP_001156907.1 893 100680 T47 G R F Q I L K T I T H P R L C
Chimpanzee Pan troglodytes XP_526648 893 100716 T47 G R F Q I L K T I T H P R L C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545015 893 100744 T47 G R F Q I L K T I T H P R L C
Cat Felis silvestris
Mouse Mus musculus Q8BM85 762 86353
Rat Rattus norvegicus NP_001127985 860 96794 T47 G R F Q V L K T I T H P R L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510722 898 101284 T47 G R F Q I L K T V T H P R L C
Chicken Gallus gallus Q5F361 893 100434 T47 G R F Q I L K T I T H P R L C
Frog Xenopus laevis NP_001087131 893 100210 T47 G R F Q I L K T I V H P R L C
Zebra Danio Brachydanio rerio NP_001074106 893 100952 T47 G R F Q I L K T I T H P R L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572197 819 93251 V26 A K L H P G D V C G S N G L P
Honey Bee Apis mellifera XP_393033 792 90269
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199652 877 98431 V54 G R F Q E L R V L H H P R L C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32491 506 56739
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 96.7 N.A. 81 90.5 N.A. 90.3 87.1 81.5 76.7 N.A. 43.6 47.5 N.A. 55.2
Protein Similarity: 100 99.7 N.A. 98.8 N.A. 83.5 94.2 N.A. 94.5 92.8 90 87.6 N.A. 58.5 62.7 N.A. 70.8
P-Site Identity: 100 100 N.A. 100 N.A. 0 93.3 N.A. 93.3 100 93.3 100 N.A. 6.6 0 N.A. 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 0 100 N.A. 100 100 93.3 100 N.A. 13.3 0 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 32.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 70 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 70 0 0 0 0 8 0 0 0 8 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 8 70 0 0 0 0 % H
% Ile: 0 0 0 0 54 0 0 0 54 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 62 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 70 0 0 8 0 0 0 0 77 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 70 0 0 8 % P
% Gln: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 70 0 0 0 0 8 0 0 0 0 0 70 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 62 0 54 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 0 16 8 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _