KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCK
All Species:
26.97
Human Site:
T497
Identified Species:
49.44
UniProt:
Q8TEA7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEA7
NP_001156907.1
893
100680
T497
Y
D
A
I
D
K
D
T
P
I
P
T
D
R
Q
Chimpanzee
Pan troglodytes
XP_526648
893
100716
T497
Y
D
A
I
D
K
D
T
P
I
P
T
D
R
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545015
893
100744
T497
Y
D
A
I
D
K
D
T
P
I
P
T
D
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM85
762
86353
R391
S
L
C
Q
L
R
N
R
L
K
D
V
G
G
E
Rat
Rattus norvegicus
NP_001127985
860
96794
Q480
V
D
I
P
R
C
H
Q
Y
D
E
L
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510722
898
101284
T502
Y
D
A
I
D
K
D
T
P
I
P
T
D
R
Q
Chicken
Gallus gallus
Q5F361
893
100434
T497
Y
D
A
I
D
K
D
T
P
I
P
T
D
R
Q
Frog
Xenopus laevis
NP_001087131
893
100210
T497
Y
D
M
I
D
K
D
T
P
I
P
T
D
R
Q
Zebra Danio
Brachydanio rerio
NP_001074106
893
100952
T497
Y
D
S
I
D
K
D
T
P
I
P
T
D
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572197
819
93251
V448
W
A
A
L
L
E
V
V
P
N
G
S
Y
A
K
Honey Bee
Apis mellifera
XP_393033
792
90269
L421
G
A
V
W
A
A
L
L
G
I
T
G
D
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199652
877
98431
I504
L
L
G
V
E
G
D
I
Q
A
N
Y
D
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32491
506
56739
I135
E
L
L
S
S
A
P
I
S
T
K
L
S
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
96.7
N.A.
81
90.5
N.A.
90.3
87.1
81.5
76.7
N.A.
43.6
47.5
N.A.
55.2
Protein Similarity:
100
99.7
N.A.
98.8
N.A.
83.5
94.2
N.A.
94.5
92.8
90
87.6
N.A.
58.5
62.7
N.A.
70.8
P-Site Identity:
100
100
N.A.
100
N.A.
0
6.6
N.A.
100
100
93.3
93.3
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
20
6.6
N.A.
100
100
93.3
100
N.A.
46.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
47
0
8
16
0
0
0
8
0
0
0
16
0
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
62
0
0
54
0
62
0
0
8
8
0
70
0
0
% D
% Glu:
8
0
0
0
8
8
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
8
0
0
8
0
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
54
0
0
0
16
0
62
0
0
0
8
16
% I
% Lys:
0
0
0
0
0
54
0
0
0
8
8
0
0
0
8
% K
% Leu:
8
24
8
8
16
0
8
8
8
0
0
16
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
8
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
8
0
62
0
54
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
62
% Q
% Arg:
0
0
0
0
8
8
0
8
0
0
0
0
0
54
0
% R
% Ser:
8
0
8
8
8
0
0
0
8
0
0
8
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
54
0
8
8
54
0
0
0
% T
% Val:
8
0
8
8
0
0
8
8
0
0
0
8
0
0
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _