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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTD1 All Species: 32.73
Human Site: S179 Identified Species: 51.43
UniProt: Q8TEA8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TEA8 NP_543010.3 209 23424 S179 K T R A K G P S E S S K E R N
Chimpanzee Pan troglodytes XP_514535 305 33719 S275 K T R A K G P S E S S K E R N
Rhesus Macaque Macaca mulatta XP_001089216 289 31694 S259 K T R A K G P S E S S K E R N
Dog Lupus familis XP_849659 288 32579 S258 K T R A K G P S E S S K E R N
Cat Felis silvestris
Mouse Mus musculus Q9DD18 209 23366 S179 K T R A K G P S E S S K E R N
Rat Rattus norvegicus NP_001102064 174 19618 E144 N D G P V T I E L E S P A P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520416 395 44660 S197 E I E S G R V S Q V E E K P G
Chicken Gallus gallus XP_415023 207 23233 S176 K T R T K V P S E S S R E R N
Frog Xenopus laevis NP_001086626 207 23315 S176 K T R T K T Q S E S S R E K S
Zebra Danio Brachydanio rerio NP_001003440 207 22991 S176 K T R S K G P S D S S R E K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650072 158 17870 Y129 K D G K F G A Y M Q V H I E N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001041168 150 16739 K121 K K A Y K A D K I Q D G K F A
Sea Urchin Strong. purpuratus XP_796744 329 36416 A179 S G T K T P V A V V K A Q P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193582 153 16901 K124 A Y N P D A V K D G V F G A M
Baker's Yeast Sacchar. cerevisiae Q07648 150 16727 E121 L R S D L G E E K V K D G E F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.1 71.9 69 N.A. 95.2 73.6 N.A. 40 87.5 79.9 76.5 N.A. 48.3 N.A. 41.1 40.4
Protein Similarity: 100 68.1 72.3 70.8 N.A. 98.5 79.4 N.A. 47 94.2 91.8 88.5 N.A. 59.3 N.A. 53.1 52.8
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 6.6 80 60 66.6 N.A. 20 N.A. 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 40 86.6 80 93.3 N.A. 20 N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 39.2 34.4 N.A.
Protein Similarity: N.A. N.A. N.A. 55.9 48.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 34 0 14 7 7 0 0 0 7 7 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 7 0 7 0 14 0 7 7 0 0 0 % D
% Glu: 7 0 7 0 0 0 7 14 47 7 7 7 54 14 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 7 0 7 7 % F
% Gly: 0 7 14 0 7 54 0 0 0 7 0 7 14 0 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 7 0 7 0 0 0 7 0 0 % I
% Lys: 67 7 0 14 60 0 0 14 7 0 14 34 14 14 7 % K
% Leu: 7 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 47 % N
% Pro: 0 0 0 14 0 7 47 0 0 0 0 7 0 20 0 % P
% Gln: 0 0 0 0 0 0 7 0 7 14 0 0 7 0 0 % Q
% Arg: 0 7 54 0 0 7 0 0 0 0 0 20 0 40 0 % R
% Ser: 7 0 7 14 0 0 0 60 0 54 60 0 0 0 7 % S
% Thr: 0 54 7 14 7 14 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 7 7 20 0 7 20 14 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _