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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3RF2
All Species:
17.88
Human Site:
S291
Identified Species:
43.7
UniProt:
Q8TEC5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEC5
NP_689763.3
729
79251
S291
T
L
R
R
G
P
G
S
R
R
K
V
P
G
Q
Chimpanzee
Pan troglodytes
XP_001152752
888
93108
D294
S
T
A
P
K
H
S
D
T
K
K
N
T
K
K
Rhesus Macaque
Macaca mulatta
XP_001099248
729
79200
S291
T
L
R
R
G
P
G
S
R
R
K
G
P
G
Q
Dog
Lupus familis
XP_535227
733
79690
S294
T
L
R
R
G
P
G
S
R
R
K
G
P
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZT2
735
80048
S293
S
L
R
K
S
P
G
S
R
R
K
G
S
G
Q
Rat
Rattus norvegicus
Q498M5
735
79862
S294
T
L
R
K
S
P
G
S
R
R
K
G
S
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512137
735
79601
S296
T
F
C
G
T
V
E
S
R
R
K
S
P
R
Q
Chicken
Gallus gallus
XP_414662
602
65017
V179
F
P
A
S
S
V
Q
V
I
K
Q
L
P
L
P
Frog
Xenopus laevis
Q6NRD3
826
88022
D290
G
N
S
Q
K
Q
A
D
A
K
K
N
T
K
K
Zebra Danio
Brachydanio rerio
A5D8S5
867
91614
E296
G
S
Q
K
A
P
G
E
K
K
N
S
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33
96
90
N.A.
80.9
81.2
N.A.
67.7
48.1
34.5
32.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47
98.2
93
N.A.
89.2
88.9
N.A.
76.7
58.2
51.3
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
66.6
73.3
N.A.
46.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
80
80
N.A.
46.6
26.6
26.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
10
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
10
30
0
60
0
0
0
0
40
0
50
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
30
20
0
0
0
10
40
80
0
10
30
20
% K
% Leu:
0
50
0
0
0
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
20
0
0
0
% N
% Pro:
0
10
0
10
0
60
0
0
0
0
0
0
50
0
10
% P
% Gln:
0
0
10
10
0
10
10
0
0
0
10
0
0
0
60
% Q
% Arg:
0
0
50
30
0
0
0
0
60
60
0
0
0
10
10
% R
% Ser:
20
10
10
10
30
0
10
60
0
0
0
20
20
0
0
% S
% Thr:
50
10
0
0
10
0
0
0
10
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
20
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _