KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3RF2
All Species:
8.18
Human Site:
S472
Identified Species:
20
UniProt:
Q8TEC5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEC5
NP_689763.3
729
79251
S472
V
S
S
Q
G
S
I
S
E
G
D
P
R
Q
S
Chimpanzee
Pan troglodytes
XP_001152752
888
93108
G537
M
V
S
P
S
T
A
G
G
P
A
Q
K
L
Q
Rhesus Macaque
Macaca mulatta
XP_001099248
729
79200
S472
V
S
S
Q
G
S
I
S
E
G
D
P
R
Q
S
Dog
Lupus familis
XP_535227
733
79690
E476
S
S
Q
G
S
I
S
E
G
D
P
R
Q
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZT2
735
80048
A478
V
S
S
Q
G
S
F
A
E
G
D
P
R
Q
S
Rat
Rattus norvegicus
Q498M5
735
79862
F478
S
V
S
S
Q
G
S
F
S
E
G
D
P
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512137
735
79601
S478
A
S
S
Q
G
S
V
S
D
S
G
P
R
Q
S
Chicken
Gallus gallus
XP_414662
602
65017
G345
G
S
E
D
A
P
R
G
T
P
A
Q
V
S
A
Frog
Xenopus laevis
Q6NRD3
826
88022
A490
V
T
P
T
P
P
G
A
P
C
Q
K
L
P
V
Zebra Danio
Brachydanio rerio
A5D8S5
867
91614
L528
I
V
S
P
S
S
A
L
G
S
M
D
L
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33
96
90
N.A.
80.9
81.2
N.A.
67.7
48.1
34.5
32.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47
98.2
93
N.A.
89.2
88.9
N.A.
76.7
58.2
51.3
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
86.6
6.6
N.A.
66.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
13.3
N.A.
93.3
13.3
N.A.
80
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
20
20
0
0
20
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
10
30
20
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
30
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
40
10
10
20
30
30
20
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
0
20
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
10
20
10
20
0
0
10
20
10
40
10
10
0
% P
% Gln:
0
0
10
40
10
0
0
0
0
0
10
20
10
40
20
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
10
40
10
10
% R
% Ser:
20
60
70
10
30
50
20
30
10
20
0
0
0
20
40
% S
% Thr:
0
10
0
10
0
10
0
0
10
0
0
0
0
0
0
% T
% Val:
40
30
0
0
0
0
10
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _