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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFAP1L1
All Species:
20.3
Human Site:
Y159
Identified Species:
55.83
UniProt:
Q8TED9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TED9
NP_001139809.1
768
86432
Y159
H
S
I
V
D
G
Y
Y
E
D
A
D
S
S
Y
Chimpanzee
Pan troglodytes
XP_518027
871
97529
Y262
H
S
I
V
D
G
Y
Y
E
D
A
D
S
S
Y
Rhesus Macaque
Macaca mulatta
XP_001092605
814
91012
Q162
K
G
K
S
A
P
Y
Q
W
P
S
P
E
A
G
Dog
Lupus familis
XP_546314
812
90058
Y214
H
S
I
M
D
G
Y
Y
E
D
A
D
S
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZI0
768
86619
Y159
Q
S
I
V
D
G
Y
Y
E
D
A
D
N
S
Y
Rat
Rattus norvegicus
Q8VH46
731
80733
S146
Q
C
H
H
E
E
A
S
M
D
L
V
K
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90738
729
81141
L160
D
A
K
I
C
A
F
L
L
R
K
K
R
F
G
Frog
Xenopus laevis
Q6PF55
811
90890
Y152
V
S
S
S
Y
E
S
Y
D
E
D
E
S
N
K
Zebra Danio
Brachydanio rerio
Q4V8Y7
746
84147
Y154
N
S
I
E
D
G
Y
Y
E
D
A
E
N
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.8
33.2
80.4
N.A.
88.9
45.8
N.A.
N.A.
44.5
37.2
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.1
50.1
84.8
N.A.
95.4
62.6
N.A.
N.A.
61
55.1
70.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
6.6
N.A.
N.A.
0
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
13.3
N.A.
N.A.
20
46.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
12
12
0
0
0
56
0
0
12
12
% A
% Cys:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
56
0
0
0
12
67
12
45
0
12
0
% D
% Glu:
0
0
0
12
12
23
0
0
56
12
0
23
12
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% F
% Gly:
0
12
0
0
0
56
0
0
0
0
0
0
0
0
23
% G
% His:
34
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
56
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
23
0
0
0
0
0
0
0
12
12
12
0
12
% K
% Leu:
0
0
0
0
0
0
0
12
12
0
12
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
23
23
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% P
% Gln:
23
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% R
% Ser:
0
67
12
23
0
0
12
12
0
0
12
0
45
45
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
0
0
34
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
67
67
0
0
0
0
0
0
56
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _