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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND1A
All Species:
14.24
Human Site:
S906
Identified Species:
39.17
UniProt:
Q8TEH3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEH3
NP_065997.1
1009
110577
S906
M
P
M
G
T
H
T
S
P
L
Q
P
L
G
P
Chimpanzee
Pan troglodytes
XP_528425
1184
128972
S1081
M
P
M
G
T
H
T
S
P
L
Q
P
L
G
P
Rhesus Macaque
Macaca mulatta
XP_001086550
368
38113
I276
P
A
V
A
P
S
R
I
R
T
L
P
L
A
R
Dog
Lupus familis
XP_852113
1040
113798
S941
M
P
M
G
A
H
T
S
P
L
Q
P
L
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K382
1016
111520
S911
I
P
M
G
A
H
T
S
P
L
Q
P
L
G
P
Rat
Rattus norvegicus
A1L1I3
614
65494
N523
T
P
S
Q
M
V
A
N
A
F
C
S
A
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506128
788
87890
E697
S
P
A
K
L
G
F
E
P
D
A
L
K
S
P
Chicken
Gallus gallus
XP_422194
839
93195
H747
S
S
V
R
S
S
D
H
F
A
S
L
E
N
F
Frog
Xenopus laevis
Q68F67
1010
112359
S884
P
T
P
G
I
Y
H
S
P
R
P
L
T
S
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.7
34.5
82.8
N.A.
88.4
20.1
N.A.
38.9
40.3
63.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.7
34.5
86.2
N.A.
91.9
31.8
N.A.
52.7
52.9
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
93.3
N.A.
86.6
6.6
N.A.
20
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
13.3
N.A.
20
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
23
0
12
0
12
12
12
0
12
23
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
12
12
0
0
0
0
12
% F
% Gly:
0
0
0
56
0
12
0
0
0
0
0
0
0
45
0
% G
% His:
0
0
0
0
0
45
12
12
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
0
45
12
34
56
0
0
% L
% Met:
34
0
45
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% N
% Pro:
23
67
12
0
12
0
0
0
67
0
12
56
0
0
56
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
45
0
0
0
12
% Q
% Arg:
0
0
0
12
0
0
12
0
12
12
0
0
0
0
12
% R
% Ser:
23
12
12
0
12
23
0
56
0
0
12
12
0
23
0
% S
% Thr:
12
12
0
0
23
0
45
0
0
12
0
0
12
0
0
% T
% Val:
0
0
23
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _