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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPC4AP
All Species:
20.61
Human Site:
Y125
Identified Species:
50.37
UniProt:
Q8TEL6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEL6
NP_056453.1
797
90852
Y125
K
L
T
Q
E
T
T
Y
P
N
T
Y
I
F
D
Chimpanzee
Pan troglodytes
XP_514600
789
90011
Y125
K
L
T
Q
E
T
T
Y
P
N
T
Y
I
F
D
Rhesus Macaque
Macaca mulatta
XP_001101083
735
84595
C112
S
D
E
M
S
K
D
C
L
S
I
L
Y
N
T
Dog
Lupus familis
XP_851670
789
89961
Y125
K
L
T
Q
E
T
T
Y
P
N
T
Y
I
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV2
797
90708
Y125
K
F
T
Q
E
A
T
Y
P
N
T
Y
I
F
D
Rat
Rattus norvegicus
NP_001094218
797
90714
Y125
K
F
T
Q
E
A
T
Y
P
N
T
Y
I
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034406
771
88294
Y112
E
S
T
F
P
N
T
Y
T
F
D
L
F
G
G
Frog
Xenopus laevis
NP_001089843
772
88421
Y112
E
L
P
Y
P
N
T
Y
T
F
D
L
F
G
G
Zebra Danio
Brachydanio rerio
NP_571644
774
88849
T114
Q
E
S
T
F
P
N
T
Y
T
F
D
L
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781318
894
100381
K132
C
V
K
S
N
E
S
K
P
A
E
G
S
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
91.9
97.9
N.A.
97.6
97.7
N.A.
N.A.
82.9
78.6
72.1
N.A.
N.A.
N.A.
N.A.
40.2
Protein Similarity:
100
99
91.9
98.3
N.A.
98.1
98.6
N.A.
N.A.
90.5
87.9
84.9
N.A.
N.A.
N.A.
N.A.
57.6
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
N.A.
20
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
86.6
86.6
N.A.
N.A.
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
0
0
0
10
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
20
10
0
0
50
% D
% Glu:
20
10
10
0
50
10
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
20
0
10
10
0
0
0
0
20
10
0
20
60
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
20
30
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
50
0
0
% I
% Lys:
50
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
40
0
0
0
0
0
0
10
0
0
30
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
20
10
0
0
50
0
0
0
10
0
% N
% Pro:
0
0
10
0
20
10
0
0
60
0
0
0
0
0
10
% P
% Gln:
10
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
10
10
0
10
0
0
10
0
0
10
10
0
% S
% Thr:
0
0
60
10
0
30
70
10
20
10
50
0
0
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
70
10
0
0
50
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _