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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOK4 All Species: 31.52
Human Site: T93 Identified Species: 77.04
UniProt: Q8TEW6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TEW6 NP_060580.2 326 37028 T93 D D S A R T F T C D S E L E A
Chimpanzee Pan troglodytes XP_001147877 365 41149 T93 D D S A R T F T C D S E L E A
Rhesus Macaque Macaca mulatta XP_001098014 365 41122 T93 D D S A R T F T C D S E L E A
Dog Lupus familis XP_544390 326 37046 T93 D D S A R T F T C D S E L E A
Cat Felis silvestris
Mouse Mus musculus Q99KE3 325 37022 T93 D D S A R T F T C D S E L E A
Rat Rattus norvegicus Q4QQV2 480 52151 H98 L D T A Q R S H L L A A D A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509190 326 36604 T93 D D S A R T F T C D S E L E A
Chicken Gallus gallus A3R064 426 47148 V97 T T T E K N Y V L A A E Q R D
Frog Xenopus laevis NP_001080630 320 36761 T93 D D L A R T F T C D S E L E A
Zebra Danio Brachydanio rerio XP_697365 332 37872 T93 D D T S R T F T C E S E L E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 89.3 98.4 N.A. 98.1 20.4 N.A. 84.9 21.6 67.7 75 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 89.3 89.3 99.6 N.A. 98.7 33.3 N.A. 91.7 37 78.2 86.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 100 6.6 93.3 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 40 N.A. 100 33.3 93.3 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 80 0 0 0 0 0 10 20 10 0 10 90 % A
% Cys: 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 % C
% Asp: 80 90 0 0 0 0 0 0 0 70 0 0 10 0 10 % D
% Glu: 0 0 0 10 0 0 0 0 0 10 0 90 0 80 0 % E
% Phe: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 20 10 0 0 80 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 80 10 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 60 10 0 0 10 0 0 0 80 0 0 0 0 % S
% Thr: 10 10 30 0 0 80 0 80 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _