KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOK4
All Species:
17.58
Human Site:
Y286
Identified Species:
42.96
UniProt:
Q8TEW6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TEW6
NP_060580.2
326
37028
Y286
N
I
A
E
A
S
S
Y
A
G
E
G
Y
G
A
Chimpanzee
Pan troglodytes
XP_001147877
365
41149
Y286
N
I
A
E
A
S
S
Y
A
G
E
S
L
P
C
Rhesus Macaque
Macaca mulatta
XP_001098014
365
41122
Y286
N
I
A
E
A
S
S
Y
A
G
E
S
L
P
C
Dog
Lupus familis
XP_544390
326
37046
Y286
N
I
A
E
A
S
S
Y
A
G
E
G
Y
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99KE3
325
37022
Y286
N
I
A
E
A
S
S
Y
G
E
S
Y
G
A
A
Rat
Rattus norvegicus
Q4QQV2
480
52151
G439
S
G
T
T
A
G
S
G
S
K
G
S
D
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509190
326
36604
Y286
N
V
A
E
A
S
G
Y
P
G
E
V
Y
G
A
Chicken
Gallus gallus
A3R064
426
47148
E348
P
L
A
E
E
E
A
E
E
E
E
G
R
W
E
Frog
Xenopus laevis
NP_001080630
320
36761
N279
H
H
I
T
S
G
Q
N
N
A
E
S
S
S
N
Zebra Danio
Brachydanio rerio
XP_697365
332
37872
G286
A
G
V
D
S
A
N
G
D
L
Y
G
D
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
89.3
98.4
N.A.
98.1
20.4
N.A.
84.9
21.6
67.7
75
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.3
89.3
99.6
N.A.
98.7
33.3
N.A.
91.7
37
78.2
86.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
73.3
100
N.A.
60
20
N.A.
73.3
26.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
73.3
100
N.A.
60
33.3
N.A.
80
40
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
70
0
70
10
10
0
40
10
0
0
0
10
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
20
0
0
% D
% Glu:
0
0
0
70
10
10
0
10
10
20
70
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
20
10
20
10
50
10
40
10
30
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
10
0
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
10
10
10
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
0
0
0
30
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
20
60
60
0
10
0
10
40
10
10
0
% S
% Thr:
0
0
10
20
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
10
10
30
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _