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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R1
All Species:
12.42
Human Site:
S375
Identified Species:
24.85
UniProt:
Q8TF05
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF05
NP_001035847.1
950
107004
S375
S
D
L
S
V
S
N
S
S
V
I
L
E
N
T
Chimpanzee
Pan troglodytes
XP_001137826
923
104120
S348
S
D
L
S
V
S
N
S
S
V
I
L
E
N
T
Rhesus Macaque
Macaca mulatta
XP_001098202
950
106876
S375
S
D
L
S
V
S
N
S
S
V
I
L
E
N
T
Dog
Lupus familis
XP_849764
857
96779
K332
A
A
S
N
E
N
D
K
K
P
A
N
Y
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2V1
951
106280
S376
D
L
S
A
P
H
S
S
A
R
L
E
S
L
E
Rat
Rattus norvegicus
Q8VI02
951
105597
L374
A
P
H
S
S
A
R
L
D
G
T
L
E
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510959
970
109729
P395
V
T
A
E
K
I
K
P
D
T
L
T
E
R
I
Chicken
Gallus gallus
XP_423594
1070
120289
N498
D
L
S
A
H
V
D
N
D
N
F
A
T
K
L
Frog
Xenopus laevis
NP_001087069
946
107114
S376
A
T
E
D
C
T
A
S
D
S
L
V
N
F
S
Zebra Danio
Brachydanio rerio
NP_956554
913
102846
E358
E
E
P
D
V
A
E
E
G
G
G
E
Q
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782078
936
105410
W380
E
Y
S
S
F
L
F
W
R
Q
P
V
P
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38950
587
65580
P76
E
E
L
G
V
F
I
P
Y
V
G
G
V
E
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.8
83.6
N.A.
86.9
86.8
N.A.
52.8
72.1
74.5
62
N.A.
N.A.
N.A.
N.A.
43.7
Protein Similarity:
100
97.1
99.4
85.7
N.A.
92.3
91.6
N.A.
70
78.5
85.5
73.4
N.A.
N.A.
N.A.
N.A.
62.1
P-Site Identity:
100
100
100
0
N.A.
6.6
20
N.A.
6.6
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
33.3
N.A.
13.3
20
40
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
9
17
0
17
9
0
9
0
9
9
0
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
17
25
0
17
0
0
17
0
34
0
0
0
0
0
0
% D
% Glu:
25
17
9
9
9
0
9
9
0
0
0
17
42
9
9
% E
% Phe:
0
0
0
0
9
9
9
0
0
0
9
0
0
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
9
17
17
9
0
9
0
% G
% His:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
25
0
0
0
9
% I
% Lys:
0
0
0
0
9
0
9
9
9
0
0
0
0
17
0
% K
% Leu:
0
17
34
0
0
9
0
9
0
0
25
34
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
25
9
0
9
0
9
9
25
0
% N
% Pro:
0
9
9
0
9
0
0
17
0
9
9
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
9
0
0
0
9
0
% R
% Ser:
25
0
34
42
9
25
9
42
25
9
0
0
9
0
17
% S
% Thr:
0
17
0
0
0
9
0
0
0
9
9
9
9
0
25
% T
% Val:
9
0
0
0
42
9
0
0
0
34
0
17
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
9
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _