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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R1
All Species:
20.3
Human Site:
S442
Identified Species:
40.61
UniProt:
Q8TF05
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF05
NP_001035847.1
950
107004
S442
R
P
E
V
G
T
T
S
Q
D
S
A
L
L
D
Chimpanzee
Pan troglodytes
XP_001137826
923
104120
S415
R
P
E
V
G
T
T
S
Q
D
S
A
L
L
D
Rhesus Macaque
Macaca mulatta
XP_001098202
950
106876
S442
R
P
E
V
D
T
S
S
Q
D
S
A
L
L
D
Dog
Lupus familis
XP_849764
857
96779
T399
P
E
E
T
P
E
V
T
I
P
G
S
S
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2V1
951
106280
S443
R
P
D
A
G
T
S
S
P
E
A
T
P
L
D
Rat
Rattus norvegicus
Q8VI02
951
105597
E441
D
V
G
T
S
S
P
E
P
T
P
L
D
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510959
970
109729
S462
N
H
C
Q
E
L
N
S
R
V
H
F
G
N
S
Chicken
Gallus gallus
XP_423594
1070
120289
S565
L
R
E
A
G
H
S
S
Q
E
T
S
L
S
E
Frog
Xenopus laevis
NP_001087069
946
107114
A443
E
V
E
T
A
N
R
A
M
S
E
Q
E
L
Y
Zebra Danio
Brachydanio rerio
NP_956554
913
102846
S425
E
E
Q
D
R
T
P
S
S
P
A
E
Q
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782078
936
105410
T447
K
D
D
R
F
T
S
T
T
Q
F
A
M
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38950
587
65580
V143
G
E
W
F
T
A
R
V
S
A
C
G
V
F
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
98.8
83.6
N.A.
86.9
86.8
N.A.
52.8
72.1
74.5
62
N.A.
N.A.
N.A.
N.A.
43.7
Protein Similarity:
100
97.1
99.4
85.7
N.A.
92.3
91.6
N.A.
70
78.5
85.5
73.4
N.A.
N.A.
N.A.
N.A.
62.1
P-Site Identity:
100
100
86.6
6.6
N.A.
46.6
0
N.A.
6.6
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
20
N.A.
73.3
13.3
N.A.
13.3
66.6
20
33.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
9
0
9
0
9
17
34
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
17
9
9
0
0
0
0
25
0
0
9
0
34
% D
% Glu:
17
25
50
0
9
9
0
9
0
17
9
9
9
0
25
% E
% Phe:
0
0
0
9
9
0
0
0
0
0
9
9
0
9
0
% F
% Gly:
9
0
9
0
34
0
0
0
0
0
9
9
9
9
0
% G
% His:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
9
0
0
0
0
0
9
34
42
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
9
0
0
0
0
9
9
0
0
0
0
0
0
17
0
% N
% Pro:
9
34
0
0
9
0
17
0
17
17
9
0
9
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
34
9
0
9
9
17
0
% Q
% Arg:
34
9
0
9
9
0
17
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
9
34
59
17
9
25
17
9
9
17
% S
% Thr:
0
0
0
25
9
50
17
17
9
9
9
9
0
0
0
% T
% Val:
0
17
0
25
0
0
9
9
0
9
0
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _