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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP4R1 All Species: 28.79
Human Site: T101 Identified Species: 57.58
UniProt: Q8TF05 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF05 NP_001035847.1 950 107004 T101 L A D D S E P T V R A E L M E
Chimpanzee Pan troglodytes XP_001137826 923 104120 S96 F C Q E N R P S I P Y A F S K
Rhesus Macaque Macaca mulatta XP_001098202 950 106876 T101 L A D D S E P T V R A E L M E
Dog Lupus familis XP_849764 857 96779 R95 Y L L P I V V R Y L A D Q N N
Cat Felis silvestris
Mouse Mus musculus Q8K2V1 951 106280 T101 L A D D S E P T V R A E L M E
Rat Rattus norvegicus Q8VI02 951 105597 T101 L A D D S E P T V R A E L M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510959 970 109729 T108 L S E D T E P T V R T E L M E
Chicken Gallus gallus XP_423594 1070 120289 T213 L A D D S E P T V R A E L M E
Frog Xenopus laevis NP_001087069 946 107114 T101 L S E D S E P T V R A E L M E
Zebra Danio Brachydanio rerio NP_956554 913 102846 H94 E L M E Q I P H I A I F C Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782078 936 105410 M122 L S E D I E P M V R A E L M E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38950 587 65580
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.8 83.6 N.A. 86.9 86.8 N.A. 52.8 72.1 74.5 62 N.A. N.A. N.A. N.A. 43.7
Protein Similarity: 100 97.1 99.4 85.7 N.A. 92.3 91.6 N.A. 70 78.5 85.5 73.4 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 6.6 100 6.6 N.A. 100 100 N.A. 73.3 100 86.6 13.3 N.A. N.A. N.A. N.A. 73.3
P-Site Similarity: 100 40 100 13.3 N.A. 100 100 N.A. 93.3 100 100 26.6 N.A. N.A. N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 21.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 42 0 0 0 0 0 0 0 9 67 9 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 42 67 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 9 0 25 17 0 67 0 0 0 0 0 67 0 0 75 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 17 9 0 0 17 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 67 17 9 0 0 0 0 0 0 9 0 0 67 0 0 % L
% Met: 0 0 9 0 0 0 0 9 0 0 0 0 0 67 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 9 % N
% Pro: 0 0 0 9 0 0 84 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 9 0 9 0 0 0 0 0 0 0 9 9 0 % Q
% Arg: 0 0 0 0 0 9 0 9 0 67 0 0 0 0 0 % R
% Ser: 0 25 0 0 50 0 0 9 0 0 0 0 0 9 0 % S
% Thr: 0 0 0 0 9 0 0 59 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 9 9 0 67 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _