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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3TC2
All Species:
19.7
Human Site:
S974
Identified Species:
54.17
UniProt:
Q8TF17
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF17
NP_078853.2
1288
144777
S974
C
H
F
Y
S
S
V
S
P
N
P
E
A
C
I
Chimpanzee
Pan troglodytes
XP_527069
1288
144808
S974
C
H
F
Y
S
S
V
S
P
N
P
E
A
C
I
Rhesus Macaque
Macaca mulatta
XP_001104761
1288
145027
S974
C
H
F
Y
S
S
V
S
P
N
P
E
A
C
I
Dog
Lupus familis
XP_546315
1298
147088
S984
C
H
F
Y
S
S
V
S
P
N
P
K
A
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80VA5
1289
145125
S975
C
H
F
Y
S
S
V
S
P
N
P
D
A
C
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517241
1161
125512
S864
A
H
L
Q
H
G
R
S
S
D
A
I
R
C
L
Chicken
Gallus gallus
XP_424256
1287
143459
C973
C
H
F
Y
S
Q
V
C
P
S
P
Q
A
C
I
Frog
Xenopus laevis
NP_001089344
1210
137400
A908
R
N
R
T
K
E
A
A
E
H
Y
F
Q
A
L
Zebra Danio
Brachydanio rerio
XP_002664477
1397
159101
L980
S
R
H
Y
A
D
L
L
L
Y
G
Q
C
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.2
85.6
N.A.
81.6
N.A.
N.A.
26
53.8
32.2
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.2
90.4
N.A.
88.9
N.A.
N.A.
39.5
70.5
49.4
54.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
20
73.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
33.3
86.6
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
12
12
0
0
12
0
67
12
0
% A
% Cys:
67
0
0
0
0
0
0
12
0
0
0
0
12
78
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
12
0
0
34
0
0
0
% E
% Phe:
0
0
67
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% G
% His:
0
78
12
0
12
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
67
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
12
0
0
0
12
12
12
0
0
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
56
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
67
0
67
0
0
0
0
% P
% Gln:
0
0
0
12
0
12
0
0
0
0
0
23
12
0
0
% Q
% Arg:
12
12
12
0
0
0
12
0
0
0
0
0
12
0
0
% R
% Ser:
12
0
0
0
67
56
0
67
12
12
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
78
0
0
0
0
0
12
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _