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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WHAMM All Species: 9.7
Human Site: S503 Identified Species: 30.48
UniProt: Q8TF30 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF30 NP_001073904.1 809 90924 S503 R L Q Q A E E S I R Y S R Q H
Chimpanzee Pan troglodytes XP_510552 813 91232 S503 R L Q Q A E E S I R Y S R Q H
Rhesus Macaque Macaca mulatta XP_001082027 595 67675 S347 S V R N T S G S E P V A P N L
Dog Lupus familis XP_852133 592 68058 R344 E L C L N H K R A E I Q R K M
Cat Felis silvestris
Mouse Mus musculus Q571B6 793 88978 S496 R L Q Q A K Q S L R H L H Q H
Rat Rattus norvegicus NP_001124200 797 89609 N496 R L Q Q A K Q N V R H F H H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413835 771 88056 W478 R L Q Q A E E W K K R F Q Q H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NVC9 846 96361 G536 K L Q Q R Q A G A H G V S Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 70.2 55 N.A. 66.6 67.3 N.A. N.A. 54.5 N.A. 37.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 71.6 62.5 N.A. 77.5 77.3 N.A. N.A. 68.1 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 13.3 N.A. 60 46.6 N.A. N.A. 60 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 26.6 N.A. 86.6 80 N.A. N.A. 73.3 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 63 0 13 0 25 0 0 13 0 0 0 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 0 0 0 0 38 38 0 13 13 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % F
% Gly: 0 0 0 0 0 0 13 13 0 0 13 0 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 13 25 0 25 13 63 % H
% Ile: 0 0 0 0 0 0 0 0 25 0 13 0 0 0 0 % I
% Lys: 13 0 0 0 0 25 13 0 13 13 0 0 0 13 0 % K
% Leu: 0 88 0 13 0 0 0 0 13 0 0 13 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % M
% Asn: 0 0 0 13 13 0 0 13 0 0 0 0 0 13 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 13 0 0 13 0 0 % P
% Gln: 0 0 75 75 0 13 25 0 0 0 0 13 13 63 13 % Q
% Arg: 63 0 13 0 13 0 0 13 0 50 13 0 38 0 0 % R
% Ser: 13 0 0 0 0 13 0 50 0 0 0 25 13 0 0 % S
% Thr: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 13 0 0 0 0 0 0 13 0 13 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _