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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C2CD4C All Species: 20
Human Site: S140 Identified Species: 55
UniProt: Q8TF44 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF44 NP_001129735.1 421 44576 S140 Q G A M S L P S V P K A Q T S
Chimpanzee Pan troglodytes XP_523091 369 39573 S111 G F C A L L E S P H T R R K E
Rhesus Macaque Macaca mulatta XP_001108285 353 37794 E96 E G W A F L P E S P H T R R R
Dog Lupus familis XP_542222 423 44579 S140 Q G A M S L P S V P K A Q T S
Cat Felis silvestris
Mouse Mus musculus Q5HZI2 419 44596 K140 M S L P S V P K A Q T S Y G F
Rat Rattus norvegicus NP_001102755 422 44946 S140 Q G A M S L P S V P K A Q T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506634 437 46748 Y148 Q T A M S L P Y V P K A Q T S
Chicken Gallus gallus XP_425894 413 44534 T142 Q T S Y G F A T L V E S P H T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697197 421 46642 Y142 Q T A M S L P Y V P K A Q T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.3 31.8 87 N.A. 90.7 90.5 N.A. 70.7 60.3 N.A. 56.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 43.4 44.1 90.7 N.A. 93.8 93.3 N.A. 78.9 70.5 N.A. 70 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 26.6 100 N.A. 13.3 100 N.A. 86.6 6.6 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 40 100 N.A. 26.6 100 N.A. 86.6 46.6 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 56 23 0 0 12 0 12 0 0 56 0 0 0 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 0 0 0 12 12 0 0 12 0 0 0 12 % E
% Phe: 0 12 0 0 12 12 0 0 0 0 0 0 0 0 12 % F
% Gly: 12 45 0 0 12 0 0 0 0 0 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 12 0 0 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 12 0 0 56 0 0 12 0 % K
% Leu: 0 0 12 0 12 78 0 0 12 0 0 0 0 0 0 % L
% Met: 12 0 0 56 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 78 0 12 67 0 0 12 0 0 % P
% Gln: 67 0 0 0 0 0 0 0 0 12 0 0 56 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 12 23 12 12 % R
% Ser: 0 12 12 0 67 0 0 45 12 0 0 23 0 0 56 % S
% Thr: 0 34 0 0 0 0 0 12 0 0 23 12 0 56 12 % T
% Val: 0 0 0 0 0 12 0 0 56 12 0 0 0 0 0 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 23 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _