KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2CD4C
All Species:
12.12
Human Site:
S178
Identified Species:
33.33
UniProt:
Q8TF44
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF44
NP_001129735.1
421
44576
S178
G
A
L
A
Q
V
G
S
P
G
A
G
R
R
R
Chimpanzee
Pan troglodytes
XP_523091
369
39573
R149
D
A
L
L
G
T
L
R
V
P
R
A
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001108285
353
37794
L134
V
S
A
P
D
L
R
L
C
R
A
P
D
S
D
Dog
Lupus familis
XP_542222
423
44579
S178
G
A
L
A
Q
V
G
S
P
G
A
G
R
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5HZI2
419
44596
A178
A
Q
V
G
S
P
G
A
G
R
R
R
A
G
A
Rat
Rattus norvegicus
NP_001102755
422
44946
S178
G
A
L
A
Q
V
G
S
P
G
A
S
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506634
437
46748
S186
G
S
L
A
Q
A
T
S
P
G
A
Q
R
R
A
Chicken
Gallus gallus
XP_425894
413
44534
N180
A
Q
R
R
A
K
L
N
G
E
S
R
A
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697197
421
46642
N180
T
S
P
L
T
S
P
N
T
Q
R
K
S
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.3
31.8
87
N.A.
90.7
90.5
N.A.
70.7
60.3
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43.4
44.1
90.7
N.A.
93.8
93.3
N.A.
78.9
70.5
N.A.
70
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
6.6
93.3
N.A.
66.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
100
N.A.
20
93.3
N.A.
73.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
45
12
45
12
12
0
12
0
0
56
12
23
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
12
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
45
0
0
12
12
0
45
0
23
45
0
23
0
23
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
56
23
0
12
23
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
0
12
12
0
45
12
0
12
12
0
12
% P
% Gln:
0
23
0
0
45
0
0
0
0
12
0
12
0
23
0
% Q
% Arg:
0
0
12
12
0
0
12
12
0
23
34
23
45
45
34
% R
% Ser:
0
34
0
0
12
12
0
45
0
0
12
12
12
12
0
% S
% Thr:
12
0
0
0
12
12
12
0
12
0
0
0
0
0
0
% T
% Val:
12
0
12
0
0
34
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _