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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF418 All Species: 0.61
Human Site: S50 Identified Species: 3.33
UniProt: Q8TF45 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF45 NP_597717.1 676 77858 S50 S L G C W C G S E D E E A P S
Chimpanzee Pan troglodytes XP_001145156 648 74639 S43 E N W V L I S S L G C W C G S
Rhesus Macaque Macaca mulatta XP_001102643 707 80720 L55 S Q E E W E L L D A A Q R H L
Dog Lupus familis XP_541379 2183 254650 A64 S L D C W R E A D N E E T P S
Cat Felis silvestris
Mouse Mus musculus Q80W31 679 77298 K53 T V G P P L T K P E V I F K L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 49.2 23 N.A. 45.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.5 63.9 27.3 N.A. 62 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 13.3 53.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 26.6 73.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 20 0 20 20 0 20 0 0 % A
% Cys: 0 0 0 40 0 20 0 0 0 0 20 0 20 0 0 % C
% Asp: 0 0 20 0 0 0 0 0 40 20 0 0 0 0 0 % D
% Glu: 20 0 20 20 0 20 20 0 20 20 40 40 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % F
% Gly: 0 0 40 0 0 0 20 0 0 20 0 0 0 20 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % H
% Ile: 0 0 0 0 0 20 0 0 0 0 0 20 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 20 0 0 0 0 0 20 0 % K
% Leu: 0 40 0 0 20 20 20 20 20 0 0 0 0 0 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 0 0 0 0 0 20 0 0 0 0 0 % N
% Pro: 0 0 0 20 20 0 0 0 20 0 0 0 0 40 0 % P
% Gln: 0 20 0 0 0 0 0 0 0 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 20 0 0 0 0 0 0 20 0 0 % R
% Ser: 60 0 0 0 0 0 20 40 0 0 0 0 0 0 60 % S
% Thr: 20 0 0 0 0 0 20 0 0 0 0 0 20 0 0 % T
% Val: 0 20 0 20 0 0 0 0 0 0 20 0 0 0 0 % V
% Trp: 0 0 20 0 60 0 0 0 0 0 0 20 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _