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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF418
All Species:
3.64
Human Site:
Y454
Identified Species:
20
UniProt:
Q8TF45
Number Species:
4
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF45
NP_597717.1
676
77858
Y454
S
H
T
G
E
R
P
Y
E
C
R
E
C
R
K
Chimpanzee
Pan troglodytes
XP_001145156
648
74639
E427
H
T
G
E
R
P
Y
E
C
R
E
C
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001102643
707
80720
F460
V
H
T
G
E
R
P
F
E
C
S
E
C
G
R
Dog
Lupus familis
XP_541379
2183
254650
Y1281
I
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80W31
679
77298
H453
L
V
R
H
Q
R
I
H
T
G
E
K
P
Y
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
49.2
23
N.A.
45.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.5
63.9
27.3
N.A.
62
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
66.6
73.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
80
80
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
20
60
0
20
60
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
20
60
0
0
20
60
0
40
60
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
60
0
0
0
0
0
20
0
0
0
40
0
% G
% His:
20
60
0
20
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
20
0
0
0
0
0
20
0
20
40
% K
% Leu:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
20
60
0
0
0
0
0
20
0
0
% P
% Gln:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
20
0
20
60
0
0
0
20
20
0
20
20
20
% R
% Ser:
20
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% S
% Thr:
0
20
60
0
0
0
0
0
20
0
0
0
0
0
0
% T
% Val:
20
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
40
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _