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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8B4 All Species: 22.12
Human Site: S1123 Identified Species: 48.67
UniProt: Q8TF62 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF62 NP_079113.2 1192 135868 S1123 R R P R T R R S S S R R S G Y
Chimpanzee Pan troglodytes XP_510393 1192 135875 S1123 R R P R T R R S S S R R S G Y
Rhesus Macaque Macaca mulatta XP_001114383 1223 138692 T1155 C M R R V G R T G S R R S G Y
Dog Lupus familis XP_544674 1170 133079 S1101 Q R P Q T R R S S S R R S G Y
Cat Felis silvestris
Mouse Mus musculus P98199 1209 136949 T1141 C M R R V G R T G S R R S G Y
Rat Rattus norvegicus XP_001078004 1252 141774 S1183 R R P Q T R R S S S R R S G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_429208 1172 133646 H1104 A S D K V S R H F K A K K R P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687715 1223 139712 T1152 N L R R V R R T S S R R S A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396773 1378 155607 R1307 T P S T R R T R R S L R S G Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SX33 1200 136027 V1128 L I T L F V V V A T L M P Y F
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 R1268 R K V R Q V Q R M K K Q R G F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 69.1 89.9 N.A. 69.3 83.7 N.A. N.A. 63.2 N.A. 68.7 N.A. N.A. 47.9 N.A. N.A.
Protein Similarity: 100 99.8 82.4 94 N.A. 82.2 90 N.A. N.A. 78.1 N.A. 81.9 N.A. N.A. 63.1 N.A. N.A.
P-Site Identity: 100 100 53.3 86.6 N.A. 53.3 93.3 N.A. N.A. 6.6 N.A. 60 N.A. N.A. 40 N.A. N.A.
P-Site Similarity: 100 100 60 100 N.A. 60 100 N.A. N.A. 20 N.A. 66.6 N.A. N.A. 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.2 34.4 N.A.
Protein Similarity: N.A. N.A. N.A. 60.4 54.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 0 10 0 0 10 0 % A
% Cys: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 19 % F
% Gly: 0 0 0 0 0 19 0 0 19 0 0 0 0 73 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 10 0 0 0 0 0 19 10 10 10 0 0 % K
% Leu: 10 10 0 10 0 0 0 0 0 0 19 0 0 0 0 % L
% Met: 0 19 0 0 0 0 0 0 10 0 0 10 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 37 0 0 0 0 0 0 0 0 0 10 0 10 % P
% Gln: 10 0 0 19 10 0 10 0 0 0 0 10 0 0 0 % Q
% Arg: 37 37 28 55 10 55 73 19 10 0 64 73 10 10 0 % R
% Ser: 0 10 10 0 0 10 0 37 46 73 0 0 73 0 0 % S
% Thr: 10 0 10 10 37 0 10 28 0 10 0 0 0 0 0 % T
% Val: 0 0 10 0 37 19 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 73 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _