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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B4
All Species:
27.27
Human Site:
S512
Identified Species:
60
UniProt:
Q8TF62
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF62
NP_079113.2
1192
135868
S512
N
F
G
F
I
F
K
S
R
T
P
E
T
I
T
Chimpanzee
Pan troglodytes
XP_510393
1192
135875
S512
N
F
G
F
I
F
K
S
R
T
P
E
T
I
T
Rhesus Macaque
Macaca mulatta
XP_001114383
1223
138692
S545
N
F
G
F
V
F
R
S
R
T
P
K
T
I
T
Dog
Lupus familis
XP_544674
1170
133079
S491
N
F
G
F
I
F
K
S
R
T
P
E
T
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P98199
1209
136949
S531
N
F
G
F
V
F
R
S
R
T
P
K
T
I
T
Rat
Rattus norvegicus
XP_001078004
1252
141774
S572
N
F
G
F
I
F
K
S
R
T
P
E
T
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_429208
1172
133646
A513
N
F
G
F
V
F
R
A
R
T
P
E
T
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687715
1223
139712
S541
N
F
G
F
V
F
R
S
R
T
P
E
T
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396773
1378
155607
K696
R
N
F
G
F
V
F
K
E
R
S
P
N
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX33
1200
136027
A547
T
E
K
I
S
Y
E
A
E
S
P
D
E
A
A
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
K673
G
Y
K
F
I
I
R
K
G
N
S
V
T
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
69.1
89.9
N.A.
69.3
83.7
N.A.
N.A.
63.2
N.A.
68.7
N.A.
N.A.
47.9
N.A.
N.A.
Protein Similarity:
100
99.8
82.4
94
N.A.
82.2
90
N.A.
N.A.
78.1
N.A.
81.9
N.A.
N.A.
63.1
N.A.
N.A.
P-Site Identity:
100
100
80
100
N.A.
80
100
N.A.
N.A.
80
N.A.
86.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
34.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.4
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
10
0
19
0
0
55
10
0
0
% E
% Phe:
0
73
10
82
10
73
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
73
10
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
46
10
0
0
0
0
0
0
0
73
10
% I
% Lys:
0
0
19
0
0
0
37
19
0
0
0
19
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
73
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
82
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
46
0
73
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
64
0
10
19
0
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
73
0
0
82
0
73
% T
% Val:
0
0
0
0
37
10
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _