KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B4
All Species:
15.45
Human Site:
S579
Identified Species:
34
UniProt:
Q8TF62
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF62
NP_079113.2
1192
135868
S579
P
S
N
E
V
L
L
S
L
T
S
D
H
L
S
Chimpanzee
Pan troglodytes
XP_510393
1192
135875
S579
P
S
N
E
V
L
L
S
L
T
S
D
H
L
S
Rhesus Macaque
Macaca mulatta
XP_001114383
1223
138692
S612
H
S
T
Q
E
L
L
S
T
T
T
D
H
L
N
Dog
Lupus familis
XP_544674
1170
133079
N558
P
S
N
E
D
L
L
N
L
T
T
D
H
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P98199
1209
136949
S598
P
P
T
Q
E
L
L
S
S
T
T
D
H
L
N
Rat
Rattus norvegicus
XP_001078004
1252
141774
S639
P
S
N
E
D
L
L
S
L
T
S
D
H
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_429208
1172
133646
E580
P
S
C
E
S
L
K
E
E
T
T
E
H
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687715
1223
139712
F608
P
S
N
E
E
L
M
F
T
T
S
E
H
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396773
1378
155607
A763
K
G
S
E
D
I
M
A
K
T
L
E
H
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX33
1200
136027
D614
S
V
I
V
Q
E
E
D
G
K
L
L
L
L
C
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
E740
D
E
A
N
Q
Y
V
E
A
T
M
R
H
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
69.1
89.9
N.A.
69.3
83.7
N.A.
N.A.
63.2
N.A.
68.7
N.A.
N.A.
47.9
N.A.
N.A.
Protein Similarity:
100
99.8
82.4
94
N.A.
82.2
90
N.A.
N.A.
78.1
N.A.
81.9
N.A.
N.A.
63.1
N.A.
N.A.
P-Site Identity:
100
100
53.3
80
N.A.
53.3
93.3
N.A.
N.A.
46.6
N.A.
60
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
100
100
73.3
93.3
N.A.
73.3
93.3
N.A.
N.A.
66.6
N.A.
80
N.A.
N.A.
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
34.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.4
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
28
0
0
10
0
0
0
55
0
0
0
% D
% Glu:
0
10
0
64
28
10
10
19
10
0
0
28
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
73
55
0
37
0
19
10
10
100
0
% L
% Met:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
46
10
0
0
0
10
0
0
0
0
0
0
46
% N
% Pro:
64
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
19
19
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
64
10
0
10
0
0
46
10
0
37
0
0
0
37
% S
% Thr:
0
0
19
0
0
0
0
0
19
91
37
0
0
0
0
% T
% Val:
0
10
0
10
19
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _