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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHROOM3
All Species:
5.45
Human Site:
S651
Identified Species:
15
UniProt:
Q8TF72
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TF72
NP_065910.3
1995
216661
S651
E
G
L
G
Q
S
L
S
G
N
F
G
K
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094783
2001
217815
S651
E
G
V
G
Q
S
L
S
G
N
F
G
K
T
K
Dog
Lupus familis
XP_850003
2151
231029
P793
E
G
L
G
Q
S
L
P
S
N
C
G
R
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXN0
1986
214869
G645
R
Q
K
V
E
R
E
G
Q
G
Q
G
L
S
G
Rat
Rattus norvegicus
Q7TP36
1423
157971
D179
G
P
V
W
Y
V
P
D
K
K
K
A
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507067
1828
198220
V584
E
P
R
E
G
L
P
V
N
Y
L
S
G
R
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q27IV2
1788
200696
D544
S
S
Q
S
S
K
T
D
G
N
K
L
S
S
V
Zebra Danio
Brachydanio rerio
XP_002662506
1695
189259
S451
L
Q
S
K
N
D
S
S
N
S
C
I
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9P3
1576
172695
Q332
E
E
S
P
P
S
V
Q
P
L
R
I
Q
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
64.6
N.A.
71.6
25.6
N.A.
34.1
N.A.
30.7
27
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97
72.2
N.A.
78.5
38.7
N.A.
46.2
N.A.
45.9
40.6
N.A.
36.4
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
6.6
0
N.A.
6.6
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
20
13.3
N.A.
6.6
N.A.
20
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
23
0
0
0
0
0
0
12
% D
% Glu:
56
12
0
12
12
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% F
% Gly:
12
34
0
34
12
0
0
12
34
12
0
45
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% I
% Lys:
0
0
12
12
0
12
0
0
12
12
23
0
23
0
34
% K
% Leu:
12
0
23
0
0
12
34
0
0
12
12
12
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
23
45
0
0
0
0
0
% N
% Pro:
0
23
0
12
12
0
23
12
12
0
0
0
12
0
12
% P
% Gln:
0
23
12
0
34
0
0
12
12
0
12
0
12
0
0
% Q
% Arg:
12
0
12
0
0
12
0
0
0
0
12
0
12
12
12
% R
% Ser:
12
12
23
12
12
45
12
34
12
12
0
12
23
45
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
0
0
0
34
0
% T
% Val:
0
0
23
12
0
12
12
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _