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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GSG2 All Species: 10.61
Human Site: T181 Identified Species: 17.95
UniProt: Q8TF76 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF76 NP_114171.2 798 88460 T181 S P C P G S P T P R D S V I S
Chimpanzee Pan troglodytes XP_001159222 798 88213 T181 S P C P G S P T P R D S V I S
Rhesus Macaque Macaca mulatta XP_001090778 800 88544 T184 S P G P G S P T P R D R A I S
Dog Lupus familis XP_854539 781 85828 A167 S P G P G P P A P G D S V L C
Cat Felis silvestris
Mouse Mus musculus Q9Z0R0 754 84163 L163 S P G A P D P L Y A D S A V P
Rat Rattus norvegicus XP_001080273 751 84077 A162 G A P D S L N A D S T V P G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425408 823 90214 S176 L F S S H D A S L G S A A N S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686125 570 63516
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P83103 566 65304
Honey Bee Apis mellifera XP_624666 678 78345 I96 T D N D K S E I N N H K S S L
Nematode Worm Caenorhab. elegans NP_492043 949 108321 S312 S F P V F D V S L N D S C E N
Sea Urchin Strong. purpuratus XP_784842 796 89784 K178 F K L T E Q K K T V T S S S S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149827 602 67250 P20 V A S G R A R P P R V G V V Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172416 599 67912 E17 E V I K S E E E D G D I P K I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 92.2 73.1 N.A. 61.9 62.6 N.A. N.A. 42.5 N.A. 36.2 N.A. 26.3 21.2 23.1 30
Protein Similarity: 100 99.1 95 80.6 N.A. 73 72.8 N.A. N.A. 57.7 N.A. 47.7 N.A. 42.9 37.8 40.1 47.1
P-Site Identity: 100 100 80 60 N.A. 33.3 6.6 N.A. N.A. 6.6 N.A. 0 N.A. 0 6.6 20 13.3
P-Site Similarity: 100 100 80 66.6 N.A. 40 6.6 N.A. N.A. 20 N.A. 0 N.A. 0 13.3 33.3 13.3
Percent
Protein Identity: N.A. 26 N.A. 26.1 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 8 0 8 8 15 0 8 0 8 22 0 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 0 8 0 15 0 22 0 0 15 0 50 0 0 0 0 % D
% Glu: 8 0 0 0 8 8 15 8 0 0 0 0 0 8 0 % E
% Phe: 8 15 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 22 8 29 0 0 0 0 22 0 8 0 8 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 0 8 0 22 8 % I
% Lys: 0 8 0 8 8 0 8 8 0 0 0 8 0 8 0 % K
% Leu: 8 0 8 0 0 8 0 8 15 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 8 15 0 0 0 8 8 % N
% Pro: 0 36 15 29 8 8 36 8 36 0 0 0 15 0 8 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 8 0 0 29 0 8 0 0 0 % R
% Ser: 43 0 15 8 15 29 0 15 0 8 8 43 15 15 43 % S
% Thr: 8 0 0 8 0 0 0 22 8 0 15 0 0 0 0 % T
% Val: 8 8 0 8 0 0 8 0 0 8 8 8 29 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _