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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GSG2 All Species: 19.39
Human Site: T553 Identified Species: 32.82
UniProt: Q8TF76 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TF76 NP_114171.2 798 88460 T553 S G E V C N R T E G F I G L N
Chimpanzee Pan troglodytes XP_001159222 798 88213 T553 S G E V C N R T E G F I G L N
Rhesus Macaque Macaca mulatta XP_001090778 800 88544 T555 S G E V C N R T E G F I G L N
Dog Lupus familis XP_854539 781 85828 T536 S D E V Y N R T E G F I G L N
Cat Felis silvestris
Mouse Mus musculus Q9Z0R0 754 84163 L524 S V H C V Q G L Y P P L L L K
Rat Rattus norvegicus XP_001080273 751 84077 L521 S V Y C V Q G L Y P P L L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425408 823 90214 T578 S E E S M N R T V G F I S L Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686125 570 63516 L346 R G C Y P E A L L K A W D K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P83103 566 65304 P342 L V K G R Y P P H F I K L W E
Honey Bee Apis mellifera XP_624666 678 78345 E454 E V F L Y E Q E N K K S V I K
Nematode Worm Caenorhab. elegans NP_492043 949 108321 T694 D E D A W N S T P N F I E M I
Sea Urchin Strong. purpuratus XP_784842 796 89784 T552 R E G E E T M T T N F I G V N
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149827 602 67250 E378 Y D A K R G S E N D H P K E F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172416 599 67912 L375 Q G P Y D P I L I K A W E E W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 92.2 73.1 N.A. 61.9 62.6 N.A. N.A. 42.5 N.A. 36.2 N.A. 26.3 21.2 23.1 30
Protein Similarity: 100 99.1 95 80.6 N.A. 73 72.8 N.A. N.A. 57.7 N.A. 47.7 N.A. 42.9 37.8 40.1 47.1
P-Site Identity: 100 100 100 86.6 N.A. 13.3 13.3 N.A. N.A. 60 N.A. 6.6 N.A. 0 0 26.6 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 20 20 N.A. N.A. 60 N.A. 6.6 N.A. 6.6 20 40 40
Percent
Protein Identity: N.A. 26 N.A. 26.1 N.A. N.A.
Protein Similarity: N.A. 39.4 N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 0 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 8 0 0 0 15 0 0 0 0 % A
% Cys: 0 0 8 15 22 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 15 8 0 8 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 8 22 36 8 8 15 0 15 29 0 0 0 15 15 8 % E
% Phe: 0 0 8 0 0 0 0 0 0 8 50 0 0 0 15 % F
% Gly: 0 36 8 8 0 8 15 0 0 36 0 0 36 0 0 % G
% His: 0 0 8 0 0 0 0 0 8 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 0 8 50 0 8 8 % I
% Lys: 0 0 8 8 0 0 0 0 0 22 8 8 8 8 22 % K
% Leu: 8 0 0 8 0 0 0 29 8 0 0 15 22 50 0 % L
% Met: 0 0 0 0 8 0 8 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 43 0 0 15 15 0 0 0 0 36 % N
% Pro: 0 0 8 0 8 8 8 8 8 15 15 8 0 0 0 % P
% Gln: 8 0 0 0 0 15 8 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 0 15 0 36 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 0 8 0 0 15 0 0 0 0 8 8 0 0 % S
% Thr: 0 0 0 0 0 8 0 50 8 0 0 0 0 0 0 % T
% Val: 0 29 0 29 15 0 0 0 8 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 15 0 8 8 % W
% Tyr: 8 0 8 15 15 8 0 0 15 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _