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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AEN
All Species:
11.82
Human Site:
S255
Identified Species:
28.89
UniProt:
Q8WTP8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTP8
NP_073604.3
325
36350
S255
V
G
Q
H
G
H
S
S
V
E
D
A
T
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545846
324
36656
S255
A
G
Q
H
G
H
S
S
V
E
D
A
T
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZI9
336
37291
S254
V
G
H
Q
G
H
S
S
V
E
D
A
M
T
A
Rat
Rattus norvegicus
B2GUW6
332
37042
S250
V
G
H
H
G
H
S
S
V
E
D
A
M
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521432
145
16419
L80
Q
E
A
Q
K
E
I
L
K
L
L
R
G
K
V
Chicken
Gallus gallus
XP_413869
301
33587
V236
L
L
Q
K
K
I
Q
V
G
C
K
G
H
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001096663
321
36753
E254
N
E
K
A
G
F
P
E
K
Q
C
V
S
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785830
225
25708
L160
T
P
G
Q
H
L
G
L
K
S
L
A
K
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7M4
567
62783
G479
L
T
C
N
K
K
S
G
L
K
K
S
N
V
S
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
D224
H
P
K
S
L
L
R
D
T
S
R
H
L
P
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.7
N.A.
71.4
73.8
N.A.
32
47.6
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
35.6
Protein Similarity:
100
N.A.
N.A.
87.6
N.A.
78.2
79.8
N.A.
37.5
60
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
80
86.6
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
80
86.6
N.A.
0
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.8
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
0
0
50
0
0
40
% A
% Cys:
0
0
10
0
0
0
0
0
0
10
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
40
0
0
0
0
% D
% Glu:
0
20
0
0
0
10
0
10
0
40
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
40
10
0
50
0
10
10
10
0
0
10
10
0
0
% G
% His:
10
0
20
30
10
40
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
10
30
10
0
0
30
10
20
0
10
10
10
% K
% Leu:
20
10
0
0
10
20
0
20
10
10
20
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
20
0
0
0
0
10
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
30
30
0
0
10
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
0
10
0
0
50
40
0
20
0
10
10
10
20
% S
% Thr:
10
10
0
0
0
0
0
0
10
0
0
0
20
40
0
% T
% Val:
30
0
0
0
0
0
0
10
40
0
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _