KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AEN
All Species:
16.36
Human Site:
S293
Identified Species:
40
UniProt:
Q8WTP8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTP8
NP_073604.3
325
36350
S293
E
D
R
E
P
D
S
S
T
D
M
E
Q
Y
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545846
324
36656
S293
E
D
R
E
P
D
S
S
T
D
M
E
Q
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZI9
336
37291
S292
E
D
R
G
P
D
S
S
T
D
V
E
Q
Y
M
Rat
Rattus norvegicus
B2GUW6
332
37042
S288
E
D
R
G
P
D
S
S
T
D
V
E
Q
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521432
145
16419
L118
D
T
S
S
S
P
L
L
V
R
R
A
G
F
P
Chicken
Gallus gallus
XP_413869
301
33587
P274
R
S
Q
P
P
R
P
P
S
P
T
D
P
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001096663
321
36753
Y292
A
K
A
T
M
E
L
Y
K
V
V
E
R
M
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785830
225
25708
E198
K
L
V
E
D
K
W
E
E
E
L
Q
S
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7M4
567
62783
T517
N
A
M
F
I
V
C
T
G
H
G
D
T
S
I
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
S262
I
Q
E
G
E
H
S
S
V
E
D
A
R
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.7
N.A.
71.4
73.8
N.A.
32
47.6
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
35.6
Protein Similarity:
100
N.A.
N.A.
87.6
N.A.
78.2
79.8
N.A.
37.5
60
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.8
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
0
0
0
0
0
20
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
40
0
0
10
40
0
0
0
40
10
20
0
0
0
% D
% Glu:
40
0
10
30
10
10
0
10
10
20
0
50
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
30
0
0
0
0
10
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
10
10
0
0
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
20
10
0
0
10
0
0
0
0
% L
% Met:
0
0
10
0
10
0
0
0
0
0
20
0
0
10
40
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
50
10
10
10
0
10
0
0
10
0
10
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
10
40
0
0
% Q
% Arg:
10
0
40
0
0
10
0
0
0
10
10
0
20
0
0
% R
% Ser:
0
10
10
10
10
0
50
50
10
0
0
0
10
10
0
% S
% Thr:
0
10
0
10
0
0
0
10
40
0
10
0
10
10
20
% T
% Val:
0
0
10
0
0
10
0
0
20
10
30
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
40
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _