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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AEN
All Species:
15.45
Human Site:
T261
Identified Species:
37.78
UniProt:
Q8WTP8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTP8
NP_073604.3
325
36350
T261
S
S
V
E
D
A
T
T
A
M
E
L
Y
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545846
324
36656
T261
S
S
V
E
D
A
T
T
A
M
E
L
Y
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZI9
336
37291
T260
S
S
V
E
D
A
M
T
A
M
E
L
Y
Q
L
Rat
Rattus norvegicus
B2GUW6
332
37042
T256
S
S
V
E
D
A
M
T
A
M
E
L
Y
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521432
145
16419
K86
I
L
K
L
L
R
G
K
V
V
V
G
H
A
L
Chicken
Gallus gallus
XP_413869
301
33587
S242
Q
V
G
C
K
G
H
S
S
V
E
D
A
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001096663
321
36753
L260
P
E
K
Q
C
V
S
L
K
K
L
T
Q
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785830
225
25708
Y166
G
L
K
S
L
A
K
Y
L
L
G
I
D
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7M4
567
62783
V485
S
G
L
K
K
S
N
V
S
P
E
T
K
E
I
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
P230
R
D
T
S
R
H
L
P
F
R
K
L
Y
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.7
N.A.
71.4
73.8
N.A.
32
47.6
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
35.6
Protein Similarity:
100
N.A.
N.A.
87.6
N.A.
78.2
79.8
N.A.
37.5
60
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
6.6
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
20
33.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.8
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
0
0
40
0
0
0
10
30
0
% A
% Cys:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
40
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
0
10
0
40
0
0
0
0
0
0
60
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
0
10
10
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
20
% I
% Lys:
0
0
30
10
20
0
10
10
10
10
10
0
10
0
10
% K
% Leu:
0
20
10
10
20
0
10
10
10
10
10
50
0
0
50
% L
% Met:
0
0
0
0
0
0
20
0
0
40
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
0
10
20
10
% Q
% Arg:
10
0
0
0
10
10
0
0
0
10
0
0
0
30
0
% R
% Ser:
50
40
0
20
0
10
10
10
20
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
20
40
0
0
0
20
0
0
10
% T
% Val:
0
10
40
0
0
10
0
10
10
20
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _