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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AEN All Species: 2.42
Human Site: T66 Identified Species: 5.93
UniProt: Q8WTP8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTP8 NP_073604.3 325 36350 T66 P G S S P L P T P F G A A T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545846 324 36656 M66 L G P S P L P M P S E A L P G
Cat Felis silvestris
Mouse Mus musculus Q9CZI9 336 37291 P65 G L C L L P S P S Q M P A V T
Rat Rattus norvegicus B2GUW6 332 37042 P61 G L C P L P S P T Q T P A G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521432 145 16419
Chicken Gallus gallus XP_413869 301 33587 G60 G W K V S K L G L S V S P S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001096663 321 36753 T92 T S Y L P N S T Y E P S S S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785830 225 25708
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L7M4 567 62783 T171 G K S F V E L T K D I P F P V
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 I59 K R K N G S K I M D M V Y N M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 82.7 N.A. 71.4 73.8 N.A. 32 47.6 N.A. 41.2 N.A. N.A. N.A. N.A. 35.6
Protein Similarity: 100 N.A. N.A. 87.6 N.A. 78.2 79.8 N.A. 37.5 60 N.A. 56.3 N.A. N.A. N.A. N.A. 49.2
P-Site Identity: 100 N.A. N.A. 46.6 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. N.A. 46.6 N.A. 6.6 6.6 N.A. 0 20 N.A. 40 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 21.5 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. 32.8 44.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 20 30 0 30 % A
% Cys: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 0 0 10 0 0 % F
% Gly: 40 20 0 0 10 0 0 10 0 0 10 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % I
% Lys: 10 10 20 0 0 10 10 0 10 0 0 0 0 0 0 % K
% Leu: 10 20 0 20 20 20 20 0 10 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 10 10 0 20 0 0 0 10 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 0 10 10 30 20 20 20 20 0 10 30 10 20 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 20 20 10 10 30 0 10 20 0 20 10 20 0 % S
% Thr: 10 0 0 0 0 0 0 30 10 0 10 0 0 10 20 % T
% Val: 0 0 0 10 10 0 0 0 0 0 10 10 0 10 10 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _