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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AEN
All Species:
6.97
Human Site:
T74
Identified Species:
17.04
UniProt:
Q8WTP8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTP8
NP_073604.3
325
36350
T74
P
F
G
A
A
T
A
T
E
A
A
S
S
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545846
324
36656
T74
P
S
E
A
L
P
G
T
E
A
T
S
S
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZI9
336
37291
E73
S
Q
M
P
A
V
T
E
A
S
D
S
R
R
Q
Rat
Rattus norvegicus
B2GUW6
332
37042
E69
T
Q
T
P
A
G
T
E
A
S
G
N
R
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521432
145
16419
Chicken
Gallus gallus
XP_413869
301
33587
S68
L
S
V
S
P
S
A
S
P
N
D
I
V
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001096663
321
36753
Q100
Y
E
P
S
S
S
A
Q
A
Y
S
R
T
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785830
225
25708
T10
V
Y
C
E
S
S
N
T
H
K
P
Y
S
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7M4
567
62783
S179
K
D
I
P
F
P
V
S
Y
Y
T
L
S
Q
K
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
N67
M
D
M
V
Y
N
M
N
K
E
I
S
K
H
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.7
N.A.
71.4
73.8
N.A.
32
47.6
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
35.6
Protein Similarity:
100
N.A.
N.A.
87.6
N.A.
78.2
79.8
N.A.
37.5
60
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
53.3
N.A.
13.3
6.6
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
53.3
N.A.
26.6
26.6
N.A.
0
40
N.A.
40
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.8
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
30
0
30
0
30
20
10
0
0
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
20
0
0
0
0
% D
% Glu:
0
10
10
10
0
0
0
20
20
10
0
0
0
0
10
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
10
0
0
0
10
0
0
30
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
10
10
0
0
10
10
30
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% L
% Met:
10
0
20
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
10
10
0
10
0
10
0
0
0
% N
% Pro:
20
0
10
30
10
20
0
0
10
0
10
0
0
0
0
% P
% Gln:
0
20
0
0
0
0
0
10
0
0
0
0
0
10
20
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
20
10
10
% R
% Ser:
10
20
0
20
20
30
0
20
0
20
10
40
40
10
0
% S
% Thr:
10
0
10
0
0
10
20
30
0
0
20
0
10
0
10
% T
% Val:
10
0
10
10
0
10
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
10
0
0
0
10
20
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _