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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK7
All Species:
12.66
Human Site:
S547
Identified Species:
21.43
UniProt:
Q8WTQ7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTQ7
NP_631948.1
553
62212
S547
E
E
G
N
S
S
K
S
G
V
C
L
L
L
_
Chimpanzee
Pan troglodytes
XP_526333
553
62171
S547
G
E
G
N
S
S
K
S
G
V
C
L
L
L
_
Rhesus Macaque
Macaca mulatta
XP_001112570
553
62224
S547
G
E
G
N
S
S
K
S
G
V
C
L
L
L
_
Dog
Lupus familis
XP_542813
553
62196
S547
G
D
G
N
S
S
K
S
G
V
C
L
L
L
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
Q541
S
P
D
L
N
R
S
Q
P
P
E
P
P
K
K
Rat
Rattus norvegicus
Q62833
590
67764
Q541
S
P
D
L
N
R
S
Q
P
P
E
P
P
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
P548
P
D
D
M
R
D
G
P
G
E
D
E
T
A
S
Chicken
Gallus gallus
XP_426681
551
62925
A543
G
Y
A
N
G
G
E
A
K
S
G
V
C
L
L
Frog
Xenopus laevis
NP_001131051
551
62674
K544
G
G
G
N
S
G
E
K
S
G
V
C
S
I
L
Zebra Danio
Brachydanio rerio
NP_001027011
549
62214
K542
G
G
S
D
D
D
K
K
S
G
T
C
T
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
A669
T
P
D
L
Q
I
N
A
A
P
E
P
D
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
D572
V
M
W
N
L
R
P
D
G
I
N
M
D
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42818
465
52569
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
M805
M
N
N
S
H
S
Q
M
D
F
D
G
D
Q
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
85.7
N.A.
41.8
42.2
N.A.
47.9
72.8
68.7
60.2
N.A.
38.2
N.A.
39.4
N.A.
Protein Similarity:
100
99.4
98
92.7
N.A.
60.6
60.6
N.A.
65.8
84.2
82.8
75.9
N.A.
54.3
N.A.
57.6
N.A.
P-Site Identity:
100
92.8
92.8
85.7
N.A.
0
0
N.A.
6.6
13.3
20
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
92.8
92.8
92.8
N.A.
6.6
6.6
N.A.
13.3
33.3
33.3
20
N.A.
6.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
15
8
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
29
15
8
0
0
% C
% Asp:
0
15
29
8
8
15
0
8
8
0
15
0
22
0
0
% D
% Glu:
8
22
0
0
0
0
15
0
0
8
22
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
43
15
36
0
8
15
8
0
43
15
8
8
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
36
15
8
0
0
0
0
22
15
% K
% Leu:
0
0
0
22
8
0
0
0
0
0
0
29
29
43
22
% L
% Met:
8
8
0
8
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
8
8
50
15
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
8
22
0
0
0
0
8
8
15
22
0
22
15
0
0
% P
% Gln:
0
0
0
0
8
0
8
15
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
8
22
0
0
0
0
0
0
0
0
8
% R
% Ser:
15
0
8
8
36
36
15
29
15
8
0
0
8
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
15
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
29
8
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% _