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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP19
All Species:
16.97
Human Site:
S116
Identified Species:
28.72
UniProt:
Q8WTR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTR2
NP_001135786.1
217
24194
S116
D
F
T
Y
K
S
I
S
I
L
D
L
P
E
T
Chimpanzee
Pan troglodytes
XP_001160131
223
24886
I116
S
S
F
T
F
F
L
I
S
F
I
N
T
P
E
Rhesus Macaque
Macaca mulatta
XP_001102671
217
24150
S116
D
F
T
Y
K
S
I
S
I
L
D
L
P
E
T
Dog
Lupus familis
XP_545555
232
25423
S116
D
F
I
Y
K
S
I
S
I
L
D
L
P
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4T5
220
24162
I116
F
T
Y
K
T
I
S
I
L
D
V
P
E
T
N
Rat
Rattus norvegicus
Q63340
280
30650
Q156
G
G
E
F
T
Y
K
Q
I
P
I
S
D
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
P227
H
Y
Q
Y
K
C
I
P
V
E
D
N
H
K
A
Frog
Xenopus laevis
NP_001089209
216
24333
S116
E
F
T
Y
K
K
I
S
I
L
D
L
P
E
T
Zebra Danio
Brachydanio rerio
XP_001331709
205
22490
T116
P
E
L
F
T
Y
K
T
V
S
M
L
D
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036572
203
22830
T114
W
P
L
P
V
N
C
T
F
L
P
C
L
D
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497538
227
25938
D133
K
F
E
Y
L
Q
I
D
I
L
D
L
P
E
T
Sea Urchin
Strong. purpuratus
XP_001200447
215
24421
I120
F
T
Y
K
N
L
P
I
W
D
L
P
E
V
K
Poplar Tree
Populus trichocarpa
XP_002332403
176
19426
D88
I
G
V
T
D
R
N
D
T
N
L
R
Q
Y
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001118683
201
22169
Y113
E
D
T
N
L
E
M
Y
F
D
E
C
V
D
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99
76.7
N.A.
81.3
28.5
N.A.
N.A.
20
67.7
58.5
N.A.
37.7
N.A.
36.1
35
Protein Similarity:
100
87
100
83.6
N.A.
91.3
38.9
N.A.
N.A.
32.7
80.1
73.2
N.A.
52.5
N.A.
52.4
54.3
P-Site Identity:
100
0
100
93.3
N.A.
0
6.6
N.A.
N.A.
26.6
86.6
6.6
N.A.
6.6
N.A.
66.6
0
P-Site Similarity:
100
6.6
100
93.3
N.A.
6.6
13.3
N.A.
N.A.
46.6
93.3
26.6
N.A.
26.6
N.A.
66.6
0
Percent
Protein Identity:
34.5
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
50.6
N.A.
N.A.
50.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
15
0
0
0
% C
% Asp:
22
8
0
0
8
0
0
15
0
22
43
0
15
15
0
% D
% Glu:
15
8
15
0
0
8
0
0
0
8
8
0
15
36
8
% E
% Phe:
15
36
8
15
8
8
0
0
15
8
0
0
0
0
15
% F
% Gly:
8
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
8
0
8
0
0
8
43
22
43
0
15
0
0
0
0
% I
% Lys:
8
0
0
15
36
8
15
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
15
0
15
8
8
0
8
43
15
43
8
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
8
0
0
8
0
15
0
0
8
% N
% Pro:
8
8
0
8
0
0
8
8
0
8
8
15
36
8
8
% P
% Gln:
0
0
8
0
0
8
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
8
0
0
0
22
8
29
8
8
0
8
0
0
0
% S
% Thr:
0
15
29
15
22
0
0
15
8
0
0
0
8
8
36
% T
% Val:
0
0
8
0
8
0
0
0
15
0
8
0
8
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% W
% Tyr:
0
8
15
43
0
15
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _