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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP19 All Species: 16.06
Human Site: S127 Identified Species: 27.18
UniProt: Q8WTR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTR2 NP_001135786.1 217 24194 S127 L P E T N I L S Y F P E C F E
Chimpanzee Pan troglodytes XP_001160131 223 24886 V127 N T P E K N I V Y F F P P A L
Rhesus Macaque Macaca mulatta XP_001102671 217 24150 S127 L P E T N I L S Y F P E C F E
Dog Lupus familis XP_545555 232 25423 S127 L P E T N I L S Y F P E C F E
Cat Felis silvestris
Mouse Mus musculus Q8K4T5 220 24162 Y127 P E T N I L S Y F P E C F E F
Rat Rattus norvegicus Q63340 280 30650 L167 S D H W S Q N L S Q F F P E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PW71 375 41034 S238 N H K A D I S S W F M E A I E
Frog Xenopus laevis NP_001089209 216 24333 S127 L P E T D I A S F F P E C F N
Zebra Danio Brachydanio rerio XP_001331709 205 22490 I127 L D L P E T D I T A Y F P E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036572 203 22830 N125 C L D L P E T N L M N Y I L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_497538 227 25938 D144 L P E T R I I D Y F E R V F E
Sea Urchin Strong. purpuratus XP_001200447 215 24421 F131 P E V K I T K F F K Y A I D F
Poplar Tree Populus trichocarpa XP_002332403 176 19426 F99 R Q Y F D K C F N F I D E A K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001118683 201 22169 A124 C V D F I D E A K R Q G G S V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 99 76.7 N.A. 81.3 28.5 N.A. N.A. 20 67.7 58.5 N.A. 37.7 N.A. 36.1 35
Protein Similarity: 100 87 100 83.6 N.A. 91.3 38.9 N.A. N.A. 32.7 80.1 73.2 N.A. 52.5 N.A. 52.4 54.3
P-Site Identity: 100 13.3 100 100 N.A. 0 0 N.A. N.A. 33.3 73.3 6.6 N.A. 0 N.A. 60 0
P-Site Similarity: 100 20 100 100 N.A. 13.3 6.6 N.A. N.A. 53.3 86.6 6.6 N.A. 13.3 N.A. 66.6 6.6
Percent
Protein Identity: 34.5 N.A. N.A. 31.3 N.A. N.A.
Protein Similarity: 50.6 N.A. N.A. 50.6 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 8 8 0 8 0 8 8 15 8 % A
% Cys: 15 0 0 0 0 0 8 0 0 0 0 8 29 0 8 % C
% Asp: 0 15 15 0 22 8 8 8 0 0 0 8 0 8 0 % D
% Glu: 0 15 36 8 8 8 8 0 0 0 15 36 8 22 36 % E
% Phe: 0 0 0 15 0 0 0 15 22 58 15 15 8 36 15 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % G
% His: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 22 43 15 8 0 0 8 0 15 8 0 % I
% Lys: 0 0 8 8 8 8 8 0 8 8 0 0 0 0 8 % K
% Leu: 43 8 8 8 0 8 22 8 8 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % M
% Asn: 15 0 0 8 22 8 8 8 8 0 8 0 0 0 8 % N
% Pro: 15 36 8 8 8 0 0 0 0 8 29 8 22 0 8 % P
% Gln: 0 8 0 0 0 8 0 0 0 8 8 0 0 0 0 % Q
% Arg: 8 0 0 0 8 0 0 0 0 8 0 8 0 0 0 % R
% Ser: 8 0 0 0 8 0 15 36 8 0 0 0 0 8 0 % S
% Thr: 0 8 8 36 0 15 8 0 8 0 0 0 0 0 0 % T
% Val: 0 8 8 0 0 0 0 8 0 0 0 0 8 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 8 36 0 15 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _