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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP19
All Species:
20.61
Human Site:
S178
Identified Species:
34.87
UniProt:
Q8WTR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTR2
NP_001135786.1
217
24194
S178
T
S
F
T
S
A
F
S
L
V
K
N
A
R
P
Chimpanzee
Pan troglodytes
XP_001160131
223
24886
S184
T
S
F
T
S
A
F
S
L
V
K
N
A
R
P
Rhesus Macaque
Macaca mulatta
XP_001102671
217
24150
S178
T
S
F
T
S
A
F
S
L
V
K
N
A
R
P
Dog
Lupus familis
XP_545555
232
25423
S178
L
S
F
T
S
A
F
S
L
V
K
N
A
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4T5
220
24162
S177
A
T
F
T
T
A
L
S
L
V
K
E
A
R
P
Rat
Rattus norvegicus
Q63340
280
30650
D220
L
S
L
N
D
A
Y
D
F
V
K
R
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
E289
V
K
L
E
K
A
F
E
F
V
K
Q
R
R
S
Frog
Xenopus laevis
NP_001089209
216
24333
S178
I
N
F
A
R
A
F
S
I
V
K
N
A
R
P
Zebra Danio
Brachydanio rerio
XP_001331709
205
22490
F166
S
A
S
V
V
I
G
F
L
M
S
E
L
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036572
203
22830
G165
R
S
P
S
V
V
I
G
Y
L
M
Q
R
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497538
227
25938
N185
V
V
A
Y
L
M
K
N
L
K
I
S
C
R
E
Sea Urchin
Strong. purpuratus
XP_001200447
215
24421
A174
Y
I
L
A
D
E
R
A
R
I
S
K
T
L
E
Poplar Tree
Populus trichocarpa
XP_002332403
176
19426
R138
L
M
K
R
H
G
M
R
L
S
E
A
L
A
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001118683
201
22169
Q163
M
T
L
A
Q
A
L
Q
H
V
K
S
K
R
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99
76.7
N.A.
81.3
28.5
N.A.
N.A.
20
67.7
58.5
N.A.
37.7
N.A.
36.1
35
Protein Similarity:
100
87
100
83.6
N.A.
91.3
38.9
N.A.
N.A.
32.7
80.1
73.2
N.A.
52.5
N.A.
52.4
54.3
P-Site Identity:
100
100
100
93.3
N.A.
66.6
26.6
N.A.
N.A.
33.3
66.6
6.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
40
N.A.
N.A.
33.3
80
33.3
N.A.
26.6
N.A.
26.6
13.3
Percent
Protein Identity:
34.5
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
50.6
N.A.
N.A.
50.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
22
0
65
0
8
0
0
0
8
43
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
15
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
0
8
0
8
0
0
8
15
0
0
15
% E
% Phe:
0
0
43
0
0
0
43
8
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
0
8
8
0
8
8
8
0
0
0
0
% I
% Lys:
0
8
8
0
8
0
8
0
0
8
65
8
15
15
0
% K
% Leu:
22
0
29
0
8
0
15
0
58
8
0
0
15
8
0
% L
% Met:
8
8
0
0
0
8
8
0
0
8
8
0
0
0
8
% M
% Asn:
0
8
0
8
0
0
0
8
0
0
0
36
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
50
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
15
0
0
0
% Q
% Arg:
8
0
0
8
8
0
8
8
8
0
0
8
15
72
0
% R
% Ser:
8
43
8
8
29
0
0
43
0
8
15
15
0
0
15
% S
% Thr:
22
15
0
36
8
0
0
0
0
0
0
0
8
0
0
% T
% Val:
15
8
0
8
15
8
0
0
0
65
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _