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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP19 All Species: 9.09
Human Site: S191 Identified Species: 15.38
UniProt: Q8WTR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTR2 NP_001135786.1 217 24194 S191 R P S I C P N S G F M E Q L R
Chimpanzee Pan troglodytes XP_001160131 223 24886 S197 R P S I C P N S G F M E Q L R
Rhesus Macaque Macaca mulatta XP_001102671 217 24150 S191 R P S I C P N S G F M E Q L R
Dog Lupus familis XP_545555 232 25423 A191 R P S I C P N A G F M E Q L R
Cat Felis silvestris
Mouse Mus musculus Q8K4T5 220 24162 P190 R P S I C P N P G F M E Q L R
Rat Rattus norvegicus Q63340 280 30650 F233 K S N I S P N F N F M G Q L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PW71 375 41034 F302 R S I I S P N F S F M G Q L L
Frog Xenopus laevis NP_001089209 216 24333 P191 R P A A C P N P G F M E Q L H
Zebra Danio Brachydanio rerio XP_001331709 205 22490 F179 K M S F D E A F S V A K T S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036572 203 22830 A178 R D M C Y E D A Y N L V K S W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_497538 227 25938 R198 R E A M D K C R E T R S I R P
Sea Urchin Strong. purpuratus XP_001200447 215 24421 R187 L E E I R V H R P C V R P N E
Poplar Tree Populus trichocarpa XP_002332403 176 19426 P151 A H V K S K R P Q A G P N S G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001118683 201 22169 A176 R P V A S P N A G F I R Q L Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 99 76.7 N.A. 81.3 28.5 N.A. N.A. 20 67.7 58.5 N.A. 37.7 N.A. 36.1 35
Protein Similarity: 100 87 100 83.6 N.A. 91.3 38.9 N.A. N.A. 32.7 80.1 73.2 N.A. 52.5 N.A. 52.4 54.3
P-Site Identity: 100 100 100 93.3 N.A. 93.3 46.6 N.A. N.A. 53.3 73.3 13.3 N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 60 N.A. N.A. 53.3 80 26.6 N.A. 33.3 N.A. 20 20
Percent
Protein Identity: 34.5 N.A. N.A. 31.3 N.A. N.A.
Protein Similarity: 50.6 N.A. N.A. 50.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 15 0 0 8 22 0 8 8 0 0 0 0 % A
% Cys: 0 0 0 8 43 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 15 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 15 8 0 0 15 0 0 8 0 0 43 0 0 8 % E
% Phe: 0 0 0 8 0 0 0 22 0 65 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 50 0 8 15 0 0 8 % G
% His: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 8 58 0 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 15 0 0 8 0 15 0 0 0 0 0 8 8 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 0 0 8 0 0 65 15 % L
% Met: 0 8 8 8 0 0 0 0 0 0 58 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 65 0 8 8 0 0 8 8 0 % N
% Pro: 0 50 0 0 0 65 0 22 8 0 0 8 8 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 65 0 8 % Q
% Arg: 72 0 0 0 8 0 8 15 0 0 8 15 0 8 43 % R
% Ser: 0 15 43 0 29 0 0 22 15 0 0 8 0 22 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % T
% Val: 0 0 15 0 0 8 0 0 0 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _