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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP19
All Species:
17.88
Human Site:
T199
Identified Species:
30.26
UniProt:
Q8WTR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTR2
NP_001135786.1
217
24194
T199
G
F
M
E
Q
L
R
T
Y
Q
E
G
K
E
S
Chimpanzee
Pan troglodytes
XP_001160131
223
24886
T205
G
F
M
E
Q
L
R
T
Y
Q
E
G
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001102671
217
24150
T199
G
F
M
E
Q
L
R
T
Y
Q
E
G
K
E
S
Dog
Lupus familis
XP_545555
232
25423
T199
G
F
M
E
Q
L
R
T
Y
Q
Q
G
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4T5
220
24162
T198
G
F
M
E
Q
L
R
T
Y
Q
V
G
K
E
S
Rat
Rattus norvegicus
Q63340
280
30650
D241
N
F
M
G
Q
L
L
D
F
E
R
T
L
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
Q310
S
F
M
G
Q
L
L
Q
F
E
S
Q
V
L
A
Frog
Xenopus laevis
NP_001089209
216
24333
K199
G
F
M
E
Q
L
H
K
Y
Q
E
T
V
R
R
Zebra Danio
Brachydanio rerio
XP_001331709
205
22490
P187
S
V
A
K
T
S
R
P
Q
I
Q
P
N
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036572
203
22830
R186
Y
N
L
V
K
S
W
R
P
C
I
Q
P
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497538
227
25938
N206
E
T
R
S
I
R
P
N
T
G
F
A
Q
Q
L
Sea Urchin
Strong. purpuratus
XP_001200447
215
24421
G195
P
C
V
R
P
N
E
G
F
M
R
Q
L
E
E
Poplar Tree
Populus trichocarpa
XP_002332403
176
19426
F159
Q
A
G
P
N
S
G
F
I
S
Q
L
Q
D
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001118683
201
22169
D184
G
F
I
R
Q
L
Q
D
L
E
K
S
M
Q
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99
76.7
N.A.
81.3
28.5
N.A.
N.A.
20
67.7
58.5
N.A.
37.7
N.A.
36.1
35
Protein Similarity:
100
87
100
83.6
N.A.
91.3
38.9
N.A.
N.A.
32.7
80.1
73.2
N.A.
52.5
N.A.
52.4
54.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
N.A.
26.6
60
6.6
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
40
N.A.
N.A.
46.6
60
20
N.A.
20
N.A.
13.3
20
Percent
Protein Identity:
34.5
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
50.6
N.A.
N.A.
50.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
15
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
43
0
0
8
0
0
22
29
0
0
43
8
% E
% Phe:
0
65
0
0
0
0
0
8
22
0
8
0
0
0
8
% F
% Gly:
50
0
8
15
0
0
8
8
0
8
0
36
0
8
15
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
8
8
8
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
0
8
0
0
8
0
36
0
0
% K
% Leu:
0
0
8
0
0
65
15
0
8
0
0
8
15
8
15
% L
% Met:
0
0
58
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
8
8
0
0
8
8
0
8
0
0
0
0
8
8
0
% N
% Pro:
8
0
0
8
8
0
8
8
8
0
0
8
8
8
0
% P
% Gln:
8
0
0
0
65
0
8
8
8
43
22
22
15
15
0
% Q
% Arg:
0
0
8
15
0
8
43
8
0
0
15
0
0
8
8
% R
% Ser:
15
0
0
8
0
22
0
0
0
8
8
8
0
0
36
% S
% Thr:
0
8
0
0
8
0
0
36
8
0
0
15
0
0
0
% T
% Val:
0
8
8
8
0
0
0
0
0
0
8
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
43
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _