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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP19
All Species:
30.91
Human Site:
T27
Identified Species:
52.31
UniProt:
Q8WTR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTR2
NP_001135786.1
217
24194
T27
C
T
R
V
T
T
L
T
G
K
K
I
I
E
T
Chimpanzee
Pan troglodytes
XP_001160131
223
24886
T27
C
T
R
V
T
T
L
T
G
K
K
I
I
E
T
Rhesus Macaque
Macaca mulatta
XP_001102671
217
24150
T27
C
T
R
V
T
T
L
T
G
K
K
I
I
E
T
Dog
Lupus familis
XP_545555
232
25423
T27
C
T
R
V
T
S
L
T
G
R
T
T
V
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4T5
220
24162
T27
C
T
R
V
T
T
L
T
G
K
K
L
I
E
T
Rat
Rattus norvegicus
Q63340
280
30650
G67
S
P
P
T
S
V
L
G
L
G
G
L
R
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
Y138
Y
E
R
F
A
S
E
Y
P
E
F
C
A
K
T
Frog
Xenopus laevis
NP_001089209
216
24333
S27
C
T
R
I
T
T
L
S
G
K
R
I
I
E
T
Zebra Danio
Brachydanio rerio
XP_001331709
205
22490
S27
S
T
R
V
T
T
A
S
G
Q
V
L
L
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036572
203
22830
T25
A
T
V
V
T
T
P
T
G
V
R
Y
I
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497538
227
25938
D44
G
E
Y
E
E
I
Q
D
S
G
E
D
L
V
D
Sea Urchin
Strong. purpuratus
XP_001200447
215
24421
L31
R
E
D
E
T
R
V
L
E
A
R
N
A
S
G
Poplar Tree
Populus trichocarpa
XP_002332403
176
19426
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001118683
201
22169
Y24
S
L
P
G
I
E
K
Y
N
E
K
V
K
N
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99
76.7
N.A.
81.3
28.5
N.A.
N.A.
20
67.7
58.5
N.A.
37.7
N.A.
36.1
35
Protein Similarity:
100
87
100
83.6
N.A.
91.3
38.9
N.A.
N.A.
32.7
80.1
73.2
N.A.
52.5
N.A.
52.4
54.3
P-Site Identity:
100
100
100
66.6
N.A.
93.3
6.6
N.A.
N.A.
13.3
80
53.3
N.A.
53.3
N.A.
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
26.6
N.A.
N.A.
33.3
100
80
N.A.
60
N.A.
13.3
20
Percent
Protein Identity:
34.5
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
50.6
N.A.
N.A.
50.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
0
0
8
0
0
15
0
0
% A
% Cys:
43
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
8
% D
% Glu:
0
22
0
15
8
8
8
0
8
15
8
0
0
58
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
8
58
15
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
8
0
0
0
0
0
29
43
8
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
36
36
0
8
8
0
% K
% Leu:
0
8
0
0
0
0
50
8
8
0
0
22
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% N
% Pro:
0
8
15
0
0
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
8
% Q
% Arg:
8
0
58
0
0
8
0
0
0
8
22
0
8
0
8
% R
% Ser:
22
0
0
0
8
15
0
15
8
0
0
0
0
8
8
% S
% Thr:
0
58
0
8
65
50
0
43
0
0
8
8
0
0
58
% T
% Val:
0
0
8
50
0
8
8
0
0
8
8
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
15
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _