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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP19
All Species:
13.64
Human Site:
Y128
Identified Species:
23.08
UniProt:
Q8WTR2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTR2
NP_001135786.1
217
24194
Y128
P
E
T
N
I
L
S
Y
F
P
E
C
F
E
F
Chimpanzee
Pan troglodytes
XP_001160131
223
24886
Y128
T
P
E
K
N
I
V
Y
F
F
P
P
A
L
V
Rhesus Macaque
Macaca mulatta
XP_001102671
217
24150
Y128
P
E
T
N
I
L
S
Y
F
P
E
C
F
E
F
Dog
Lupus familis
XP_545555
232
25423
Y128
P
E
T
N
I
L
S
Y
F
P
E
C
F
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4T5
220
24162
F128
E
T
N
I
L
S
Y
F
P
E
C
F
E
F
I
Rat
Rattus norvegicus
Q63340
280
30650
S168
D
H
W
S
Q
N
L
S
Q
F
F
P
E
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PW71
375
41034
W239
H
K
A
D
I
S
S
W
F
M
E
A
I
E
Y
Frog
Xenopus laevis
NP_001089209
216
24333
F128
P
E
T
D
I
A
S
F
F
P
E
C
F
N
F
Zebra Danio
Brachydanio rerio
XP_001331709
205
22490
T128
D
L
P
E
T
D
I
T
A
Y
F
P
E
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036572
203
22830
L126
L
D
L
P
E
T
N
L
M
N
Y
I
L
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497538
227
25938
Y145
P
E
T
R
I
I
D
Y
F
E
R
V
F
E
F
Sea Urchin
Strong. purpuratus
XP_001200447
215
24421
F132
E
V
K
I
T
K
F
F
K
Y
A
I
D
F
I
Poplar Tree
Populus trichocarpa
XP_002332403
176
19426
N100
Q
Y
F
D
K
C
F
N
F
I
D
E
A
K
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001118683
201
22169
K125
V
D
F
I
D
E
A
K
R
Q
G
G
S
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99
76.7
N.A.
81.3
28.5
N.A.
N.A.
20
67.7
58.5
N.A.
37.7
N.A.
36.1
35
Protein Similarity:
100
87
100
83.6
N.A.
91.3
38.9
N.A.
N.A.
32.7
80.1
73.2
N.A.
52.5
N.A.
52.4
54.3
P-Site Identity:
100
13.3
100
100
N.A.
0
0
N.A.
N.A.
33.3
73.3
6.6
N.A.
0
N.A.
60
0
P-Site Similarity:
100
20
100
100
N.A.
13.3
6.6
N.A.
N.A.
60
86.6
6.6
N.A.
13.3
N.A.
66.6
6.6
Percent
Protein Identity:
34.5
N.A.
N.A.
31.3
N.A.
N.A.
Protein Similarity:
50.6
N.A.
N.A.
50.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
8
0
8
0
8
8
15
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
8
29
0
8
0
% C
% Asp:
15
15
0
22
8
8
8
0
0
0
8
0
8
0
0
% D
% Glu:
15
36
8
8
8
8
0
0
0
15
36
8
22
36
0
% E
% Phe:
0
0
15
0
0
0
15
22
58
15
15
8
36
15
43
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
22
43
15
8
0
0
8
0
15
8
0
22
% I
% Lys:
0
8
8
8
8
8
0
8
8
0
0
0
0
8
0
% K
% Leu:
8
8
8
0
8
22
8
8
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
8
22
8
8
8
8
0
8
0
0
0
8
0
% N
% Pro:
36
8
8
8
0
0
0
0
8
29
8
22
0
8
0
% P
% Gln:
8
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
8
% R
% Ser:
0
0
0
8
0
15
36
8
0
0
0
0
8
0
0
% S
% Thr:
8
8
36
0
15
8
0
8
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
0
0
8
0
0
0
0
8
0
8
8
% V
% Trp:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
36
0
15
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _