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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD7 All Species: 26.67
Human Site: S221 Identified Species: 97.78
UniProt: Q8WTS6 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTS6 NP_085151.1 366 40721 S221 E R V Y V A E S L I S S A G E
Chimpanzee Pan troglodytes XP_001138145 776 84508 S631 E R V Y V A E S L I S S A G E
Rhesus Macaque Macaca mulatta XP_001088778 692 75818 S547 E R V Y V A E S L I S S A G E
Dog Lupus familis XP_533287 504 55198 S359 E R V Y V A E S L I S S A G E
Cat Felis silvestris
Mouse Mus musculus Q8VHL1 366 40488 S221 E R V Y V A D S L I S S A G E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513516 360 39872 S215 E R V Y V A E S L I S T A G E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DHG0 373 41494 S221 Q R V Y V G Q S L I S G A G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47 52.8 70.8 N.A. 95.3 N.A. N.A. 90.7 N.A. N.A. 71.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.1 52.8 72.2 N.A. 99.1 N.A. N.A. 94.8 N.A. N.A. 84.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 93.3 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 N.A. N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 86 0 0 0 0 0 0 100 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % D
% Glu: 86 0 0 0 0 0 72 0 0 0 0 0 0 0 100 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 15 0 0 0 0 0 15 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 15 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % Q
% Arg: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 100 72 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % T
% Val: 0 0 100 0 100 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _